Patient P-02115
Synthetic patientMETA-24 · Day 92 · 35–44 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
76%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 67 SC-12 recommended — Supportive Compound SC-12
- Day 68 Patient accepted — Started SC-12 in the companion
- Day 71 GI-04 recommended — GI Support Protocol GI-04
- Day 72 Patient accepted — Started GI-04 in the companion
- Day 74 GI symptom burden −21% vs expected — Supportive Compound SC-12
- Day 80 GI symptom burden −33% vs expected — GI Support Protocol GI-04
- Day 80 Tolerance state changed — Unstable → Improving
- Day 86 Tolerance state changed — Unstable → Improving
- Day 88 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 88.
Primary contributors, last 14 days
- GI instability+24
- Nutritional resilience-20
- Inflammatory activity+17
- Toxicity+11
- Treatment adherence-5
What helped?
- Supportive Compound SC-12Day 67Result: symptom burden −21%
- GI Support Protocol GI-04Day 71Result: symptom burden −33%
LIFE OS recommendation
Hydration Protocol HY-01
61%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 63% showed improvement
- median effect visible after 4 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable25 min
worsening · -4.4 vs previous 14 d
Sleep duration
Wearable7.3 h
stable · -0.2 vs previous 14 d
Energy level
Daily log4.3/10
stable · -0.2 vs previous 14 d
Steps
Wearable2,466
worsening · -303 vs previous 14 d
GI burden
Companion47/100
worsening · +4.4 vs previous 14 d
Adherence
Companion90.8 %
improving · +4.7 vs previous 14 d
Sleep quality
Wearable49/100
worsening · -4.0 vs previous 14 d
Glucose, CGM daily mean
CGM131 mg/dL
stable · +4.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 59 from the failing basin, 39 from restoration.
Would help
- HY-01 Hydration Protocol63% improved among 8 similar · onset 4 d · confidence 78%
- More proteinGI -6 next day on high-intake days · n 22
Would not help
- Keep fat lowGI +5.5 next day on high-intake days · n 25
- Keep ultra-processed lowGI +5.4 next day on high-intake days · n 26
- Keep histamine lowGI +5 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6supporter · 95%
- Dietary fat load+5.5detractor · 95%
- Ultra-processed food+5.4detractor · 95%
- Histamine load+5detractor · 95%
- Simple carbohydrates+3.2detractor · 95%
- Caffeine-1.9no signal · 43%
- Insoluble fibre+0.6no signal · 15%
- Alcohol-0.6no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 48
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 27/100
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 47 and rising
- Autonomic recovery ↓45
- WearableResting HR 78 bpm
- Wearable2,466 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 40
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.4 · butyrate capacity 27/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 44 ms
- Sleep
- 7.0 h
- Steps
- 3,015
- Resting HR
- 75 bpm
Daily log: GI score 47, nutritional resilience 44, adherence 91.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02483 | 30% | S06 | BR-03 | no change | 64 |
| P-02013 | 29% | S14 | BR-03 | no change | 94 |
| P-02282 | 27% | S01 | BR-03 | no change | 88 |
| P-02233 | 31% | S16 | CR-01 | improved | 66 |
| P-02193 | 29% | S11 | CR-01 | improved | 87 |
| P-02354 | 29% | S01 | CR-01 | improved | 78 |
| P-02009 | 27% | S08 | CR-01 | improved | 64 |
| P-02491 | 30% | S09 | DT-01 | no change | 65 |
| P-02462 | 29% | S12 | DT-01 | improved | 65 |
| P-02081 | 27% | S20 | DT-01 | no change | 88 |
| P-02395 | 27% | S12 | DT-01 | improved | 57 |
| P-02518 | 27% | S17 | DT-01 | improved | 68 |