Patient P-02129
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
16%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S09
- Day 13 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 13.
Primary contributors, last 14 days
- Treatment adherence-9
- Toxicity+5
- Inflammatory activity+4
- Nutritional resilience-3
- GI instability-2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable71 min
stable · +0.8 vs previous 14 d
Sleep duration
Wearable6.2 h
stable · +0.2 vs previous 14 d
Energy level
Daily log4.9/10
stable · +0.1 vs previous 14 d
Steps
Wearable7,985
improving · +523 vs previous 14 d
GI burden
Companion19.7/100
stable · +0.2 vs previous 14 d
Adherence
Companion83.9 %
stable · -1.3 vs previous 14 d
Sleep quality
Wearable35.9/100
improving · +4.7 vs previous 14 d
Glucose, CGM daily mean
CGM126 mg/dL
stable · -3.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 63 from the failing basin, 52 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -2.8 next day on high-intake days · n 27
Would not help
- BR-03 Behavioural Recommendationonly 30% improved among 10 similar
- Keep histamine lowGI +3.2 next day on high-intake days · n 19
- Keep simple carbs lowGI +2.1 next day on high-intake days · n 19
- Keep alcohol lowGI +2 next day on high-intake days · n 15
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+3.2detractor · 95%
- Protein-2.8supporter · 95%
- Simple carbohydrates+2.1detractor · 79%
- Alcohol+2detractor · 76%
- Ultra-processed food+1.4detractor · 55%
- Dietary fat load+1.3no signal · 28%
- Insoluble fibre+0.2no signal · 15%
- Caffeine0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Autonomic recovery ↓20
- WearableShort sleep window
- Inflammatory signalling ↑15
- WearableHRV 34 ms, trending down
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.9 · butyrate capacity 66/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 6.5 h
- Steps
- 7,389
- Resting HR
- 61 bpm
Daily log: GI score 20, nutritional resilience 64, adherence 84.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.