Patient P-02552
Therapy response
Unstable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
22%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S07
- Day 23 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 28 AD-05 recommended — Adherence Support AD-05
- Day 29 Patient accepted — Started AD-05 in the companion
- Day 34 No meaningful change — Adherence Support AD-05
What changed?
Trajectory began diverging from predicted response on Day 23.
Primary contributors, last 14 days
- Toxicity-11
- GI instability+6
- Nutritional resilience+5
- Treatment adherence+3
What helped?
- Adherence Support AD-05Day 28Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑40
- DNAIL6 -174 variant raises baseline inflammatory tone
- WearableHRV 29 ms, trending down
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.6 · butyrate capacity 66/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 30 ms
- Sleep
- 7.1 h
- Steps
- 7,240
- Resting HR
- 62 bpm
Daily log: GI score 24, nutritional resilience 64, adherence 85.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.