700 patients110,866 observations180 daysLIVE

Patient P-02156

Synthetic patientMETA-24 · Day 97 · 65–74 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
34%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S14
  2. Day 16 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 16.

Primary contributors, last 14 days
  • GI instability+10
  • Nutritional resilience+4
  • Toxicity-4
  • Inflammatory activity-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    76 min
    improving · +4.3 vs previous 14 d
    Sleep duration
    Wearable
    7.7 h
    stable · +0.2 vs previous 14 d
    Energy level
    Daily log
    5.8/10
    stable · +0.2 vs previous 14 d
    Steps
    Wearable
    7,775
    stable · +196 vs previous 14 d
    GI burden
    Companion
    14.6/100
    worsening · +2.6 vs previous 14 d
    Adherence
    Companion
    87.4 %
    stable · +0.9 vs previous 14 d
    Sleep quality
    Wearable
    55.9/100
    improving · +3.0 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    132 mg/dL
    stable · +0.8 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 79 from the failing basin, 23 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -5.2 next day on high-intake days · n 23
    Would not help
    • Keep fat low
      GI +5.1 next day on high-intake days · n 16
    • Keep caffeine low
      GI +5 next day on high-intake days · n 21
    • Keep histamine low
      GI +4.2 next day on high-intake days · n 17
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -5.2supporter · 95%
    • Dietary fat load
      +5.1detractor · 95%
    • Caffeine
      +5detractor · 95%
    • Histamine load
      +4.2detractor · 95%
    • Alcohol
      +3.8detractor · 87%
    • Ultra-processed food
      +2.7detractor · 61%
    • Simple carbohydrates
      -1no signal · 15%
    • Insoluble fibre
      -0.4no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity 60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling 60
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 34 ms, trending down
    • Butyrate / short-chain fatty acid production 60
      • MicrobiomeButyrate capacity 44/100
      • MicrobiomeF. prausnitzii depleted
    • Drug metabolism and exposure 40
      • DNACYP2D6 poor metabolizer → higher exposure
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.1 · butyrate capacity 44/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    31 ms
    Sleep
    7.2 h
    Steps
    8,633
    Resting HR
    68 bpm
    Daily log: GI score 15, nutritional resilience 70, adherence 87.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0259054%S1461
    P-0250147%S1455
    P-0204946%S1463
    P-0235246%S1459
    P-0250046%S14GI-04no change58
    P-0207045%S1155
    P-0219045%S1462
    P-0223544%S14DT-01improved50
    P-0224344%S1461
    P-0256844%S0151
    P-0209543%S0866
    P-0212643%S16DT-01improved59