Patient P-02183
Synthetic patientMETA-24 · Day 177 · 45–54 · M · baseline S18Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
18%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S18
- Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 22 GI-04 recommended — GI Support Protocol GI-04
- Day 23 Patient accepted — Started GI-04 in the companion
- Day 31 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 16.
Primary contributors, last 14 days
- Toxicity-8
- Nutritional resilience-5
- Treatment adherence-4
- GI instability-2
What helped?
- GI Support Protocol GI-04Day 22Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable55 min
worsening · -3.4 vs previous 14 d
Sleep duration
Wearable6.5 h
stable · +0.0 vs previous 14 d
Energy level
Daily log6/10
stable · -0.1 vs previous 14 d
Steps
Wearable5,982
stable · +183 vs previous 14 d
GI burden
Companion21.9/100
worsening · +4.7 vs previous 14 d
Adherence
Companion85.9 %
stable · +0.1 vs previous 14 d
Sleep quality
Wearable42.9/100
stable · +0.3 vs previous 14 d
Glucose, CGM daily mean
CGM133 mg/dL
stable · -0.6 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 70 from the failing basin, 20 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +10.1
- GI Support Protocol GI-04intervention · steering +6.7
- Proteinsupporter · GI -5.6 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Poor metabolizerhidden · steering -12.7
- Dietary fat loadperturbation · steering -8.6
- Low microbial diversityhidden · steering -7.7
- Dietary fat loaddetractor · GI +5.2 next day
- Alcoholdetractor · GI +4.3 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.6supporter · 95%
- Dietary fat load+5.2detractor · 95%
- Alcohol+4.3detractor · 95%
- Caffeine+3.5detractor · 90%
- Ultra-processed food+2.9detractor · 85%
- Simple carbohydrates+2.3no signal · 52%
- Insoluble fibre-1.5no signal · 41%
- Histamine load+0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 38/100
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.8 · butyrate capacity 38/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 55 ms
- Sleep
- 6.8 h
- Steps
- 5,569
- Resting HR
- 71 bpm
Daily log: GI score 22, nutritional resilience 59, adherence 86.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.