Patient P-02240
Synthetic patientMETA-24 · Day 173 · 65–74 · M · baseline S20Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
42%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S20
- Day 75 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 122 GI-04 recommended — GI Support Protocol GI-04
- Day 123 Patient accepted — Started GI-04 in the companion
- Day 131 GI symptom burden −17% vs expected — GI Support Protocol GI-04
- Day 137 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 75.
Primary contributors, last 14 days
- GI instability-22
- Inflammatory activity-15
- Nutritional resilience+8
- Treatment adherence-7
- Toxicity+5
What helped?
- GI Support Protocol GI-04Day 122Result: symptom burden −17%
LIFE OS recommendation
Monitoring Escalation ME-01
69%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable78 min
improving · +4.5 vs previous 14 d
Sleep duration
Wearable7.2 h
stable · +0.1 vs previous 14 d
Energy level
Daily log4.7/10
improving · +0.5 vs previous 14 d
Steps
Wearable9,024
improving · +574 vs previous 14 d
GI burden
Companion34.3/100
improving · -12.9 vs previous 14 d
Adherence
Companion68.2 %
worsening · -5.0 vs previous 14 d
Sleep quality
Wearable34.6/100
improving · +6.1 vs previous 14 d
Glucose, CGM daily mean
CGM133 mg/dL
stable · -3.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 56 from the failing basin, 31 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 39 similar · onset 3 d · confidence 57%
- NP-02 Dietary Support Protocol63% improved among 30 similar · onset 10 d · confidence 57%
- SC-12 Supportive Compound67% improved among 27 similar · onset 6 d · confidence 57%
- More proteinGI -5.4 next day on high-intake days · n 22
Would not help
- Keep ultra-processed lowGI +6.1 next day on high-intake days · n 22
- Keep fat lowGI +5.9 next day on high-intake days · n 26
- Keep histamine lowGI +5.7 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Ultra-processed food+6.1detractor · 95%
- Dietary fat load+5.9detractor · 95%
- Histamine load+5.7detractor · 95%
- Protein-5.4supporter · 95%
- Alcohol+4.8detractor · 95%
- Caffeine+0.5no signal · 15%
- Insoluble fibre+0.4no signal · 15%
- Simple carbohydrates-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↓60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 24 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 42/100
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑20
- BloodToxicity index 51
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 3 · butyrate capacity 42/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 22 ms
- Sleep
- 7.2 h
- Steps
- 7,337
- Resting HR
- 68 bpm
Daily log: GI score 34, nutritional resilience 48, adherence 68.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02483 | 27% | S06 | BR-03 | no change | 64 |
| P-02054 | 41% | S01 | CR-01 | improved | 57 |
| P-02233 | 40% | S16 | CR-01 | improved | 66 |
| P-02151 | 36% | S04 | CR-01 | improved | 49 |
| P-02009 | 35% | S08 | CR-01 | improved | 64 |
| P-02154 | 35% | S16 | CR-01 | improved | 57 |
| P-02025 | 30% | S15 | CR-01 | improved | 61 |
| P-02339 | 26% | S03 | DT-01 | improved | 50 |
| P-02491 | 26% | S09 | DT-01 | no change | 65 |
| P-02235 | 24% | S14 | DT-01 | improved | 50 |
| P-02274 | 24% | S15 | DT-01 | improved | 50 |
| P-02395 | 24% | S12 | DT-01 | improved | 57 |