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Patient P-02245

Synthetic patientMETA-24 · Day 161 · 65–74 · F · baseline S09Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
10%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S09

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • GI instability-4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    83 min
    stable · -0.9 vs previous 14 d
    Sleep duration
    Wearable
    6.3 h
    stable · +0.1 vs previous 14 d
    Energy level
    Daily log
    5.9/10
    worsening · -0.5 vs previous 14 d
    Steps
    Wearable
    9,324
    stable · -89 vs previous 14 d
    GI burden
    Companion
    15.9/100
    stable · +0.3 vs previous 14 d
    Adherence
    Companion
    94.1 %
    stable · +1.7 vs previous 14 d
    Sleep quality
    Wearable
    36.7/100
    improving · +3.0 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    132 mg/dL
    stable · -1.7 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 94 from the failing basin, 11 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +10.6
    • Butyrate producers intact
      hidden · steering +7.5
    • Protein
      supporter · GI -6.4 next day
    Main detractors to watch
    • Histamine load
      perturbation · steering -12.9
    • Poor metabolizer
      hidden · steering -12.7
    • Caffeine
      perturbation · steering -11.1
    • FUT2 non-secretor
      hidden · steering -10.6
    • Histamine load
      detractor · GI +6.5 next day
    • Caffeine
      detractor · GI +6 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +6.5detractor · 95%
    • Protein
      -6.4supporter · 95%
    • Caffeine
      +6detractor · 95%
    • Ultra-processed food
      +5.1detractor · 94%
    • Simple carbohydrates
      +5detractor · 89%
    • Insoluble fibre
      +2.4no signal · 41%
    • Alcohol
      +1.5no signal · 18%
    • Dietary fat load
      +0.8no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Inflammatory signalling ↑35
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 31 ms, trending down
    • Mucosal barrier integrity ↓30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery ↑20
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 2.9 · butyrate capacity 77/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    31 ms
    Sleep
    6.0 h
    Steps
    9,235
    Resting HR
    67 bpm
    Daily log: GI score 16, nutritional resilience 65, adherence 94.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0233732%S18DT-01no change100
    P-0224934%S09DT-01improved100
    P-0218932%S17——96
    P-0264033%S03——96
    P-0224235%S20——95
    P-0201342%S14BR-03no change94
    P-0210443%S15——94
    P-0245041%S12NP-02improved92
    P-0230450%S15——92
    P-0227737%S05AD-05improved92
    P-0265332%S14——91
    P-0268934%S13——91