Patient P-02250
Therapy response
Improving
Tolerance
Unstable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
67%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S04
- Day 19 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 19.
Primary contributors, last 14 days
- Toxicity+14
- Inflammatory activity+6
- Nutritional resilience+5
- Treatment adherence+5
- GI instability+2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
74%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 89% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable20 min
improving · +3.5 vs previous 14 d
Sleep duration
Wearable5.9 h
improving · +0.3 vs previous 14 d
Energy level
Daily log1.9/10
improving · +0.2 vs previous 14 d
Steps
Wearable1,863
improving · +240 vs previous 14 d
GI burden
Companion68.9/100
improving · -5.7 vs previous 14 d
Adherence
Companion69.3 %
stable · +0.8 vs previous 14 d
Sleep quality
Wearable15.6/100
improving · +5.2 vs previous 14 d
Glucose, CGM daily mean
CGM157 mg/dL
stable · -0.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 40 from the failing basin, 70 from restoration.
Would help
- GI-04 GI Support Protocol77% improved among 64 similar · onset 8 d · confidence 70%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 75%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 75%
- More proteinGI -3.3 next day on high-intake days · n 21
Would not help
- Keep histamine lowGI +3.1 next day on high-intake days · n 21
- Keep ultra-processed lowGI +3 next day on high-intake days · n 22
- Keep fat lowGI +2.3 next day on high-intake days · n 29
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-3.3supporter · 95%
- Histamine load+3.1detractor · 95%
- Ultra-processed food+3detractor · 95%
- Dietary fat load+2.3detractor · 83%
- Simple carbohydrates+1.2no signal · 37%
- Caffeine-0.8no signal · 26%
- Insoluble fibre-0.6no signal · 19%
- Alcohol+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 69 and rising
- WearableSleep 5.9 h, below personal baseline
- Inflammatory signalling ↑85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 68
- WearableHRV 21 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 34/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑65
- WearableResting HR 74 bpm
- Wearable1,863 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 63
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 1.8 · butyrate capacity 34/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 20 ms
- Sleep
- 5.7 h
- Steps
- 2,466
- Resting HR
- 74 bpm
Daily log: GI score 69, nutritional resilience 35, adherence 69.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02025 | 45% | S15 | CR-01 | improved | 61 |
| P-02151 | 44% | S04 | CR-01 | improved | 49 |
| P-02165 | 36% | S14 | ME-01 | improved | 59 |
| P-02054 | 35% | S01 | CR-01 | improved | 57 |
| P-02094 | 35% | S14 | NP-02 | improved | 53 |
| P-02297 | 35% | S02 | NP-02 | improved | 49 |
| P-02320 | 35% | S14 | NP-02 | improved | 50 |
| P-02334 | 35% | S04 | GI-04 | improved | 66 |
| P-02582 | 35% | S14 | ME-01 | improved | 45 |
| P-02648 | 35% | S14 | SC-12 | improved | 47 |
| P-02057 | 34% | S14 | GI-04 | improved | 47 |
| P-02348 | 34% | S14 | GI-04 | improved | 49 |