Patient P-02277

Synthetic patientMETA-24 · Day 168 · 65–74 · M · baseline S05Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Favorable

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S05
Day 124 AD-05 recommended — Adherence Support AD-05
Day 125 Patient accepted — Started AD-05 in the companion
Day 130 GI symptom burden −17% vs expected — Adherence Support AD-05
Day 136 Tolerance state changed — Unstable → Improving

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

GI instability-6
Inflammatory activity-4
Nutritional resilience+2
Treatment adherence+2
Toxicity+2

What helped?

Adherence Support AD-05Day 124
Result: symptom burden −17%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

55 min

improving · +3.1 vs previous 14 d

Sleep duration

Wearable

7.5 h

stable · +0.2 vs previous 14 d

Energy level

Daily log

7/10

stable · +0.2 vs previous 14 d

Steps

Wearable

5,391

stable · +87 vs previous 14 d

GI burden

Companion

9.7/100

improving · -8.0 vs previous 14 d

Adherence

Companion

93.5 %

stable · -2.8 vs previous 14 d

Sleep quality

Wearable

62.1/100

improving · +5.5 vs previous 14 d

Glucose, CGM daily mean

CGM

125 mg/dL

stable · -1.9 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 101 from the failing basin, 17 from restoration.

Good elements to keep

Adherence Support AD-05
intervention · steering +24.6
Butyrate producers intact
hidden · steering +7.5
Protein (supports)
perturbation · steering +6.8
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -4.2 next day

Main detractors to watch

Poor metabolizer
hidden · steering -12.7
Bacteroides fragilis elevated
hidden · steering -7.4
Caffeine
perturbation · steering -6.9
Alcohol on dosing days
perturbation · steering -1.8
Caffeine
detractor · GI +4 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4.2supporter · 95%
Caffeine
+4detractor · 95%
Alcohol
-1.6no signal · 42%
Simple carbohydrates
-1.1no signal · 24%
Dietary fat load
+1no signal · 27%
Ultra-processed food
-1no signal · 25%
Histamine load
-0.6no signal · 15%
Insoluble fibre
-0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose
GLP1R rs6923761 A
Altered receptor sensitivity
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.4 · butyrate capacity 73/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 64 ms
Sleep: 8.2 h
Steps: 4,495
Resting HR: 55 bpm

Daily log: GI score 10, nutritional resilience 70, adherence 94.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02337	48%	S18	DT-01	no change	100
P-02249	54%	S09	DT-01	improved	100
P-02189	46%	S17	—	—	96
P-02640	46%	S03	—	—	96
P-02242	42%	S20	—	—	95
P-02013	42%	S14	BR-03	no change	94
P-02104	42%	S15	—	—	94
P-02450	51%	S12	NP-02	improved	92
P-02304	37%	S15	—	—	92
P-02653	40%	S14	—	—	91
P-02689	34%	S13	—	—	91
P-02481	50%	S05	—	—	91