Patient P-02290
Synthetic patientMETA-24 · Day 169 · 65–74 · F · baseline S12Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
14%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S12
- Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 10.
Primary contributors, last 14 days
- Toxicity-11
- Treatment adherence+7
- Inflammatory activity-5
- GI instability+2
- Nutritional resilience+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable43 min
improving · +1.9 vs previous 14 d
Sleep duration
Wearable5.7 h
stable · -0.1 vs previous 14 d
Energy level
Daily log5.9/10
worsening · -0.5 vs previous 14 d
Steps
Wearable5,546
worsening · -226 vs previous 14 d
GI burden
Companion17.8/100
worsening · +5.0 vs previous 14 d
Adherence
Companion96.4 %
stable · +0.6 vs previous 14 d
Sleep quality
Wearable37.4/100
worsening · -1.8 vs previous 14 d
Glucose, CGM daily mean
CGM136 mg/dL
worsening · +5.4 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 75 from the failing basin, 21 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +12.9
- Butyrate producers intacthidden · steering +7.5
- Proteinsupporter · GI -6.7 next day
Main detractors to watch
- Poor metabolizerhidden · steering -12.7
- Caffeineperturbation · steering -11.2
- Bacteroides fragilis elevatedhidden · steering -7.4
- Low-HRV stretchperturbation · steering -2.7
- Caffeinedetractor · GI +6.5 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.7supporter · 95%
- Caffeine+6.5detractor · 95%
- Insoluble fibre+1.4no signal · 27%
- Alcohol+1.4no signal · 21%
- Simple carbohydrates+0.8no signal · 15%
- Ultra-processed food-0.8no signal · 15%
- Dietary fat load+0.6no signal · 15%
- Histamine load-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.7 h, below personal baseline
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 3.1 · butyrate capacity 50/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 44 ms
- Sleep
- 6.3 h
- Steps
- 4,976
- Resting HR
- 62 bpm
Daily log: GI score 18, nutritional resilience 64, adherence 96.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.