Patient P-02354
Therapy response
Improving
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
31%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S01
- Day 22 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 102 CR-01 recommended — Clinician Review CR-01
- Day 103 Patient accepted — Started CR-01 in the companion
- Day 108 Deterioration detected before clinical escalation — Clinician Review CR-01
What changed?
Trajectory began diverging from predicted response on Day 22.
Primary contributors, last 14 days
- GI instability+14
- Nutritional resilience-9
- Inflammatory activity+8
- Toxicity-8
- Treatment adherence+5
What helped?
- Clinician Review CR-01Day 102Result: deterioration detected before clinical escalation
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 28 ms, trending down
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 2.8 · butyrate capacity 77/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 29 ms
- Sleep
- 5.7 h
- Steps
- 7,170
- Resting HR
- 62 bpm
Daily log: GI score 28, nutritional resilience 62, adherence 100.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02555 | 32% | S01 | AD-05 | no change | 79 |
| P-02483 | 37% | S06 | BR-03 | no change | 64 |
| P-02282 | 33% | S01 | BR-03 | no change | 88 |
| P-02518 | 44% | S17 | DT-01 | improved | 68 |
| P-02462 | 42% | S12 | DT-01 | improved | 65 |
| P-02491 | 42% | S09 | DT-01 | no change | 65 |
| P-02126 | 36% | S16 | DT-01 | improved | 59 |
| P-02218 | 35% | S01 | DT-01 | improved | 61 |
| P-02330 | 34% | S15 | DT-01 | no change | 57 |
| P-02235 | 33% | S14 | DT-01 | improved | 50 |
| P-02274 | 32% | S15 | DT-01 | improved | 50 |
| P-02417 | 32% | S18 | DT-01 | no change | 55 |