Patient P-02330

Synthetic patientMETA-24 · Day 129 · 25–34 · M · baseline S15Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Favorable

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

11%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S15
Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 DT-01 recommended — Dosing / Timing Recommendation DT-01
Day 23 Patient accepted — Started DT-01 in the companion
Day 28 No meaningful change — Dosing / Timing Recommendation DT-01

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days

GI instability-29
Inflammatory activity-21
Nutritional resilience+14
Treatment adherence-6
Toxicity+3

What helped?

Dosing / Timing Recommendation DT-01Day 22
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

72 min

improving · +7.1 vs previous 14 d

Sleep duration

Wearable

6.5 h

stable · +0.2 vs previous 14 d

Energy level

Daily log

5.6/10

improving · +0.6 vs previous 14 d

Steps

Wearable

7,854

improving · +676 vs previous 14 d

GI burden

Companion

12.7/100

improving · -7.6 vs previous 14 d

Adherence

Companion

90.3 %

worsening · -4.1 vs previous 14 d

Sleep quality

Wearable

43.5/100

improving · +3.4 vs previous 14 d

Glucose, CGM daily mean

CGM

134 mg/dL

improving · -5.9 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 83 from the failing basin, 23 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +15
Dosing / Timing Recommendation DT-01
intervention · steering +11.1
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -7.1 next day

Main detractors to watch

Low butyrate capacity
hidden · steering -17.5
Dietary fat load
perturbation · steering -10.9
Alcohol
perturbation · steering -9.3
Ultra-processed food
perturbation · steering -7.7
Dietary fat load
detractor · GI +6.9 next day
Alcohol
detractor · GI +5.6 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-7.1supporter · 95%
Dietary fat load
+6.9detractor · 95%
Alcohol
+5.6detractor · 95%
Ultra-processed food
+4.3detractor · 87%
Insoluble fibre
+2.3no signal · 39%
Simple carbohydrates
-1.4no signal · 23%
Histamine load
+0.8no signal · 15%
Caffeine
+0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 38/100
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↓40
- DNAIL6 -174 variant raises baseline inflammatory tone
- WearableHRV 35 ms, trending down
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Intermediate metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3 · butyrate capacity 38/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 33 ms
Sleep: 6.7 h
Steps: 8,647
Resting HR: 67 bpm

Daily log: GI score 13, nutritional resilience 68, adherence 90.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02030	54%	S15	—	—	56
P-02500	51%	S14	GI-04	no change	58
P-02070	49%	S11	—	—	55
P-02455	49%	S09	DT-01	improved	50
P-02219	48%	S13	—	—	60
P-02274	48%	S15	DT-01	improved	50
P-02622	47%	S07	—	—	50
P-02700	47%	S02	—	—	62
P-02049	46%	S14	—	—	63
P-02218	46%	S01	DT-01	improved	61
P-02645	46%	S02	HY-01	improved	56
P-02033	45%	S06	GI-04	improved	51