Patient P-02355
Synthetic patientMETA-24 · Day 176 · 35–44 · F · baseline S09Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Declining
Discontinuation risk
12%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S09
- Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 22 GI-04 recommended — GI Support Protocol GI-04
- Day 23 Patient accepted — Started GI-04 in the companion
- Day 31 GI symptom burden −15% vs expected — GI Support Protocol GI-04
- Day 37 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 14.
Primary contributors, last 14 days
- Nutritional resilience-8
- Inflammatory activity-7
- Toxicity-5
- GI instability+2
What helped?
- GI Support Protocol GI-04Day 22Result: symptom burden −15%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable50 min
stable · +0.7 vs previous 14 d
Sleep duration
Wearable7.3 h
stable · +0.0 vs previous 14 d
Energy level
Daily log7.1/10
worsening · -0.4 vs previous 14 d
Steps
Wearable4,705
worsening · -272 vs previous 14 d
GI burden
Companion11.1/100
worsening · +5.4 vs previous 14 d
Adherence
Companion90.6 %
stable · +2.1 vs previous 14 d
Sleep quality
Wearable57.4/100
worsening · -3.2 vs previous 14 d
Glucose, CGM daily mean
CGM127 mg/dL
stable · +1.3 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 81 from the failing basin, 24 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +12
- GI Support Protocol GI-04intervention · steering +10.1
- Proteinsupporter · GI -6.2 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Simple carbohydratesperturbation · steering -10.3
- Dietary fat loadperturbation · steering -9
- Low microbial diversityhidden · steering -7.7
- Dietary fat loaddetractor · GI +5.6 next day
- Simple carbohydratesdetractor · GI +5.5 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.2supporter · 95%
- Dietary fat load+5.6detractor · 95%
- Simple carbohydrates+5.5detractor · 95%
- Ultra-processed food+4.4detractor · 95%
- Caffeine+2.7no signal · 53%
- Insoluble fibre-1.3no signal · 26%
- Alcohol-1.3no signal · 30%
- Histamine load-1.2no signal · 28%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
- Inflammatory signalling ↓45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.6 · butyrate capacity 29/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 39 ms
- Sleep
- 7.4 h
- Steps
- 5,189
- Resting HR
- 64 bpm
Daily log: GI score 11, nutritional resilience 65, adherence 91.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.