Patient P-02357
Synthetic patientMETA-24 · Day 171 · 55–64 · F · baseline S13Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Improving
Nutritional resilience
Declining
Discontinuation risk
30%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S13
- Day 18 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 122 HY-01 recommended — Hydration Protocol HY-01
- Day 123 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 18.
Primary contributors, last 14 days
- Toxicity-21
- GI instability+12
- Treatment adherence-10
- Nutritional resilience-8
- Inflammatory activity-7
What helped?
- Hydration Protocol HY-01Day 122Declined by patient
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable78 min
worsening · -4.6 vs previous 14 d
Sleep duration
Wearable6.6 h
stable · -0.1 vs previous 14 d
Energy level
Daily log5.7/10
stable · +0.1 vs previous 14 d
Steps
Wearable8,360
worsening · -412 vs previous 14 d
GI burden
Companion21.3/100
worsening · +1.4 vs previous 14 d
Adherence
Companion87.8 %
stable · +1.1 vs previous 14 d
Sleep quality
Wearable41.8/100
worsening · -3.8 vs previous 14 d
Glucose, CGM daily mean
CGM139 mg/dL
stable · +0.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 75 from the failing basin, 17 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -3.5 next day on high-intake days · n 13
Would not help
- Keep alcohol lowGI +3.2 next day on high-intake days · n 31
- Keep histamine lowGI +2.7 next day on high-intake days · n 23
- Keep ultra-processed lowGI +2.2 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-3.5supporter · 95%
- Alcohol+3.2detractor · 95%
- Histamine load+2.7detractor · 95%
- Ultra-processed food+2.2detractor · 84%
- Simple carbohydrates+0.6no signal · 20%
- Insoluble fibre+0.5no signal · 16%
- Dietary fat load-0.2no signal · 15%
- Caffeine-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 37 ms, trending down
- Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Autonomic recovery ↓25
- WearableResting HR 73 bpm
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.8 · butyrate capacity 55/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 42 ms
- Sleep
- 6.5 h
- Steps
- 8,232
- Resting HR
- 74 bpm
Daily log: GI score 21, nutritional resilience 64, adherence 88.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.