Patient P-02377
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
21%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S19
- Day 43 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 43.
Primary contributors, last 14 days
- Treatment adherence-14
- Toxicity-12
- Inflammatory activity-11
- GI instability-9
- Nutritional resilience+9
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable50 min
worsening · -2.3 vs previous 14 d
Sleep duration
Wearable7 h
stable · -0.2 vs previous 14 d
Energy level
Daily log6.2/10
worsening · -0.3 vs previous 14 d
Steps
Wearable6,091
stable · -190 vs previous 14 d
GI burden
Companion20.2/100
worsening · +4.8 vs previous 14 d
Adherence
Companion77.6 %
worsening · -8.7 vs previous 14 d
Sleep quality
Wearable44.4/100
worsening · -5.1 vs previous 14 d
Glucose, CGM daily mean
CGM122 mg/dL
stable · +2.9 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 73 from the failing basin, 17 from restoration.
Good elements to keep
- Butyrate producers intacthidden · steering +7.5
- Protein (supports)perturbation · steering +6.5
- Proteinsupporter · GI -4 next day
Main detractors to watch
- Bacteroides fragilis elevatedhidden · steering -7.4
- IL6 high-expression varianthidden · steering -7.3
- Ultra-processed foodperturbation · steering -4.8
- Poor-sleep weekperturbation · steering -3
- Ultra-processed fooddetractor · GI +2.8 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4supporter · 95%
- Ultra-processed food+2.8detractor · 95%
- Simple carbohydrates-1.3no signal · 39%
- Dietary fat load+0.9no signal · 30%
- Insoluble fibre-0.3no signal · 15%
- Alcohol-0.3no signal · 15%
- Histamine load+0.2no signal · 15%
- Caffeine-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 4.4 · butyrate capacity 47/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 48 ms
- Sleep
- 6.5 h
- Steps
- 5,112
- Resting HR
- 65 bpm
Daily log: GI score 20, nutritional resilience 62, adherence 78.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.