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Patient P-02378

Synthetic patientMETA-24 · Day 173 · 45–54 · M · baseline S16Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
30%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S16

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • GI instability+12
  • Treatment adherence-6
  • Toxicity+5
  • Inflammatory activity+4
  • Nutritional resilience-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    60 min
    stable · -1.5 vs previous 14 d
    Sleep duration
    Wearable
    6.3 h
    stable · -0.1 vs previous 14 d
    Energy level
    Daily log
    5.6/10
    worsening · -0.6 vs previous 14 d
    Steps
    Wearable
    5,855
    worsening · -340 vs previous 14 d
    GI burden
    Companion
    24.7/100
    worsening · +7.3 vs previous 14 d
    Adherence
    Companion
    86.9 %
    stable · -0.8 vs previous 14 d
    Sleep quality
    Wearable
    42.6/100
    worsening · -6.7 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    140 mg/dL
    stable · +1.6 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 80 from the failing basin, 8 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -6.4 next day on high-intake days · n 14
    Would not help
    • Keep histamine low
      GI +4.6 next day on high-intake days · n 28
    • Keep alcohol low
      GI +4.1 next day on high-intake days · n 20
    • Keep caffeine low
      GI +3.8 next day on high-intake days · n 23
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -6.4supporter · 95%
    • Histamine load
      +4.6detractor · 95%
    • Alcohol
      +4.1detractor · 95%
    • Caffeine
      +3.8detractor · 95%
    • Ultra-processed food
      +1.8no signal · 37%
    • Simple carbohydrates
      +1.5no signal · 36%
    • Insoluble fibre
      +0.2no signal · 15%
    • Dietary fat load
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling ↑45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Autonomic recovery ↓20
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    Microbiome
    Shannon diversity 3.7 · butyrate capacity 76/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    53 ms
    Sleep
    5.9 h
    Steps
    4,820
    Resting HR
    62 bpm
    Daily log: GI score 25, nutritional resilience 66, adherence 87.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
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    P-0208139%S20DT-01no change88
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    P-0221834%S01DT-01improved61