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Patient P-02417

Synthetic patientMETA-24 · Day 179 · 65–74 · M · baseline S18Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
18%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S18
  2. Day 13 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 22 DT-01 recommended — Dosing / Timing Recommendation DT-01
  4. Day 23 Patient accepted — Started DT-01 in the companion
  5. Day 28 No meaningful change — Dosing / Timing Recommendation DT-01

What changed?

Trajectory began diverging from predicted response on Day 13.

Primary contributors, last 14 days
  • Inflammatory activity-5
  • Toxicity-4
  • GI instability+3
  • Nutritional resilience-2
  • Treatment adherence+2

What helped?

  • Dosing / Timing Recommendation DT-01Day 22
    Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
47 min
stable · -0.4 vs previous 14 d
Sleep duration
Wearable
4.9 h
stable · +0.2 vs previous 14 d
Energy level
Daily log
5.5/10
improving · +0.7 vs previous 14 d
Steps
Wearable
5,417
improving · +184 vs previous 14 d
GI burden
Companion
25.2/100
improving · -4.8 vs previous 14 d
Adherence
Companion
91.3 %
stable · -3.4 vs previous 14 d
Sleep quality
Wearable
15.1/100
improving · +3.1 vs previous 14 d
Glucose, CGM daily mean
CGM
139 mg/dL
stable · -4.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 66 from the failing basin, 25 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -5.5 next day on high-intake days · n 21
Would not help
  • DT-01 Dosing / Timing Recommendation
    already tried, no meaningful change
  • Keep ultra-processed low
    GI +4.4 next day on high-intake days · n 20
  • Keep simple carbs low
    GI +4.3 next day on high-intake days · n 18
  • Keep alcohol low
    GI +4.1 next day on high-intake days · n 17
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -5.5supporter · 95%
  • Ultra-processed food
    +4.4detractor · 95%
  • Simple carbohydrates
    +4.3detractor · 95%
  • Alcohol
    +4.1detractor · 95%
  • Insoluble fibre
    -1.9no signal · 37%
  • Dietary fat load
    -1.2no signal · 31%
  • Histamine load
    -0.8no signal · 20%
  • Caffeine
    +0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓40
    • MicrobiomeAkkermansia low → thinner mucus layer
    • WearableSleep 4.9 h, below personal baseline
  • Butyrate / short-chain fatty acid production ↓25
    • MicrobiomeF. prausnitzii depleted
  • Autonomic recovery ↑20
    • WearableShort sleep window
  • Inflammatory signalling ↓15
    • WearableHRV 35 ms, trending down
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Intermediate metabolizer
    Expected exposure
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 1.9 · butyrate capacity 48/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
31 ms
Sleep
5.8 h
Steps
4,486
Resting HR
67 bpm
Daily log: GI score 25, nutritional resilience 65, adherence 91.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0235432%S01CR-01improved78
P-0244331%S18——75
P-0269835%S06ME-01improved71
P-0255336%S13——71
P-0240331%S03——71
P-0255033%S01——70
P-0219234%S05——69
P-0221436%S08SC-12no change69
P-0235631%S08——69
P-0208337%S13——69
P-0229337%S15HY-01no change68
P-0209037%S04——68