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Patient P-02419

Synthetic patientMETA-24 · Day 169 · 35–44 · M · baseline S15Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Declining
Discontinuation risk
8%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S15

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • GI instability-8
  • Inflammatory activity-7
  • Nutritional resilience-6
  • Treatment adherence+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    73 min
    improving · +3.1 vs previous 14 d
    Sleep duration
    Wearable
    7.4 h
    stable · +0.1 vs previous 14 d
    Energy level
    Daily log
    7.3/10
    stable · -0.0 vs previous 14 d
    Steps
    Wearable
    9,005
    stable · +83 vs previous 14 d
    GI burden
    Companion
    13.5/100
    stable · +0.1 vs previous 14 d
    Adherence
    Companion
    94.7 %
    stable · -1.4 vs previous 14 d
    Sleep quality
    Wearable
    53.6/100
    stable · -0.9 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    128 mg/dL
    stable · +1.6 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 94 from the failing basin, 7 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +8.7
    • Butyrate producers intact
      hidden · steering +7.5
    • Daily walks resumed
      perturbation · steering +3.3
    • Protein
      supporter · GI -4.4 next day
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • FUT2 non-secretor
      hidden · steering -10.6
    • Histamine load
      perturbation · steering -6.6
    • Caffeine
      perturbation · steering -6.2
    • Histamine load
      detractor · GI +3.8 next day
    • Caffeine
      detractor · GI +3.6 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -4.4supporter · 95%
    • Histamine load
      +3.8detractor · 95%
    • Caffeine
      +3.6detractor · 95%
    • Simple carbohydrates
      +1no signal · 19%
    • Alcohol
      +0.8no signal · 24%
    • Ultra-processed food
      +0.8no signal · 15%
    • Insoluble fibre
      -0.1no signal · 15%
    • Dietary fat load
      0no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Mucosal barrier integrity ↓30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.2 · butyrate capacity 49/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    52 ms
    Sleep
    8.0 h
    Steps
    8,496
    Resting HR
    61 bpm
    Daily log: GI score 14, nutritional resilience 66, adherence 95.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0233740%S18DT-01no change100
    P-0224943%S09DT-01improved100
    P-0218939%S17——96
    P-0264042%S03——96
    P-0224240%S20——95
    P-0201341%S14BR-03no change94
    P-0210444%S15——94
    P-0245048%S12NP-02improved92
    P-0227751%S05AD-05improved92
    P-0230440%S15——92
    P-0265337%S14——91
    P-0268935%S13——91