Patient P-02425

Synthetic patientMETA-24 · Day 113 · 35–44 · F · baseline S07Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Deteriorating

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S07

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Toxicity+8
Nutritional resilience+5
Treatment adherence+5
GI instability-3
Inflammatory activity-2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

74 min

stable · +2.9 vs previous 14 d

Sleep duration

Wearable

6.1 h

stable · +0.1 vs previous 14 d

Energy level

Daily log

5.3/10

stable · -0.0 vs previous 14 d

Steps

Wearable

8,060

stable · +326 vs previous 14 d

GI burden

Companion

24/100

improving · -5.1 vs previous 14 d

Adherence

Companion

95.5 %

stable · -0.5 vs previous 14 d

Sleep quality

Wearable

38.5/100

improving · +5.8 vs previous 14 d

Glucose, CGM daily mean

CGM

127 mg/dL

improving · -6.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 88 from the failing basin, 8 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -4.3 next day on high-intake days · n 22

Would not help

Keep histamine low
GI +5 next day on high-intake days · n 18
Keep caffeine low
GI +4 next day on high-intake days · n 16
Keep ultra-processed low
GI +3.2 next day on high-intake days · n 15

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+5detractor · 95%
Protein
-4.3supporter · 95%
Caffeine
+4detractor · 95%
Ultra-processed food
+3.2detractor · 78%
Dietary fat load
-0.7no signal · 16%
Simple carbohydrates
-0.7no signal · 16%
Alcohol
-0.4no signal · 15%
Insoluble fibre
+0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓40
- DNAFUT2 non-secretor lowers mucosal fucosylation
- WearableSleep 6.1 h, below personal baseline
Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Inflammatory signalling ↓35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 34 ms, trending down
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Poor metabolizer
Higher exposure at standard dose
GLP1R rs6923761 A
Altered receptor sensitivity

Microbiome

Shannon diversity 4 · butyrate capacity 50/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 37 ms
Sleep: 6.4 h
Steps: 8,537
Resting HR: 57 bpm

Daily log: GI score 24, nutritional resilience 63, adherence 96.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02555	40%	S01	AD-05	no change	79
P-02277	35%	S05	AD-05	improved	92
P-02282	45%	S01	BR-03	no change	88
P-02013	39%	S14	BR-03	no change	94
P-02193	35%	S11	CR-01	improved	87
P-02354	32%	S01	CR-01	improved	78
P-02081	43%	S20	DT-01	no change	88
P-02565	36%	S09	DT-01	no change	79
P-02518	34%	S17	DT-01	improved	68
P-02249	32%	S09	DT-01	improved	100
P-02337	31%	S18	DT-01	no change	100
P-02491	31%	S09	DT-01	no change	65