Patient P-02427
Therapy response
Favorable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
19%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S08
- Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 16.
Primary contributors, last 14 days
- Treatment adherence-7
- Inflammatory activity-3
- Toxicity+3
- GI instability+2
- Nutritional resilience+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↓20
- Wearable3,125 steps/day
DNA
Fictional pharmacogenomic panel
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 4.4 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 44 ms
- Sleep
- 7.3 h
- Steps
- 3,595
- Resting HR
- 68 bpm
Daily log: GI score 21, nutritional resilience 67, adherence 90.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02518 | 47% | S17 | DT-01 | improved | 68 |
| P-02462 | 46% | S12 | DT-01 | improved | 65 |
| P-02538 | 45% | S02 | GI-04 | improved | 59 |
| P-02620 | 44% | S01 | HY-01 | improved | 64 |
| P-02698 | 43% | S06 | ME-01 | improved | 71 |
| P-02082 | 42% | S12 | NP-02 | improved | 53 |
| P-02235 | 42% | S14 | DT-01 | improved | 50 |
| P-02339 | 42% | S03 | DT-01 | improved | 50 |
| P-02147 | 41% | S13 | GI-04 | improved | 58 |
| P-02645 | 41% | S02 | HY-01 | improved | 56 |
| P-02033 | 40% | S06 | GI-04 | improved | 51 |
| P-02037 | 40% | S04 | GI-04 | improved | 53 |