Patient P-02433
Synthetic patientMETA-24 · Day 164 · 25–34 · M · baseline S07Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Stable
GI state
Deteriorating
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
65%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S07
- Day 122 GI-04 recommended — GI Support Protocol GI-04
- Day 123 Patient accepted — Started GI-04 in the companion
- Day 131 GI symptom burden −23% vs expected — GI Support Protocol GI-04
- Day 135 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 137 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 135.
Primary contributors, last 14 days
- Nutritional resilience-16
- GI instability+13
- Treatment adherence-12
- Inflammatory activity-3
What helped?
- GI Support Protocol GI-04Day 122Result: symptom burden −23%
LIFE OS recommendation
Monitoring Escalation ME-01
77%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable25 min
improving · +7.2 vs previous 14 d
Sleep duration
Wearable6.3 h
stable · -0.2 vs previous 14 d
Energy level
Daily log2.9/10
stable · -0.0 vs previous 14 d
Steps
Wearable1,885
improving · +410 vs previous 14 d
GI burden
Companion51.4/100
stable · +0.1 vs previous 14 d
Adherence
Companion66.7 %
worsening · -11.3 vs previous 14 d
Sleep quality
Wearable21.8/100
stable · +0.5 vs previous 14 d
Glucose, CGM daily mean
CGM148 mg/dL
stable · +1.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 46 from the failing basin, 45 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 41 similar · onset 3 d · confidence 65%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 65%
- SC-12 Supportive Compound69% improved among 26 similar · onset 6 d · confidence 65%
- More proteinGI -5.1 next day on high-intake days · n 17
Would not help
- Keep fat lowGI +4.8 next day on high-intake days · n 21
- Keep histamine lowGI +3.2 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.1supporter · 95%
- Dietary fat load+4.8detractor · 95%
- Histamine load+3.2detractor · 95%
- Caffeine+1.4no signal · 40%
- Alcohol+0.6no signal · 15%
- Simple carbohydrates-0.5no signal · 16%
- Ultra-processed food-0.1no signal · 15%
- Insoluble fibre0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 51 and rising
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 39/100
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓40
- BloodInflammatory load index 46
- WearableHRV 17 ms, trending down
- Autonomic recovery ↓40
- Wearable1,885 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 43
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 39/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 25 ms
- Sleep
- 6.6 h
- Steps
- 2,118
- Resting HR
- 69 bpm
Daily log: GI score 51, nutritional resilience 39, adherence 67.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02483 | 26% | S06 | BR-03 | no change | 64 |
| P-02054 | 41% | S01 | CR-01 | improved | 57 |
| P-02151 | 38% | S04 | CR-01 | improved | 49 |
| P-02233 | 37% | S16 | CR-01 | improved | 66 |
| P-02009 | 36% | S08 | CR-01 | improved | 64 |
| P-02025 | 33% | S15 | CR-01 | improved | 61 |
| P-02154 | 32% | S16 | CR-01 | improved | 57 |
| P-02354 | 24% | S01 | CR-01 | improved | 78 |
| P-02491 | 26% | S09 | DT-01 | no change | 65 |
| P-02274 | 24% | S15 | DT-01 | improved | 50 |
| P-02339 | 24% | S03 | DT-01 | improved | 50 |
| P-02395 | 24% | S12 | DT-01 | improved | 57 |