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Patient P-02434

Synthetic patientMETA-24 · Day 177 · 35–44 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Improving
Inflammatory state
Deteriorating
Nutritional resilience
Improving
Discontinuation risk
22%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S14
  2. Day 19 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 19.

Primary contributors, last 14 days
  • Nutritional resilience+10
  • GI instability-5
  • Inflammatory activity+5
  • Toxicity+3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    88 min
    worsening · -3.5 vs previous 14 d
    Sleep duration
    Wearable
    6.1 h
    worsening · -0.4 vs previous 14 d
    Energy level
    Daily log
    5.8/10
    worsening · -0.6 vs previous 14 d
    Steps
    Wearable
    9,178
    worsening · -396 vs previous 14 d
    GI burden
    Companion
    21.3/100
    worsening · +11.5 vs previous 14 d
    Adherence
    Companion
    98.5 %
    stable · +1.9 vs previous 14 d
    Sleep quality
    Wearable
    44/100
    worsening · -9.6 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    127 mg/dL
    stable · +3.7 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 77 from the failing basin, 11 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +11.3
    • Butyrate producers intact
      hidden · steering +7.5
    • Dietary fat load (supports)
      perturbation · steering +3.5
    • Protein
      supporter · GI -6.1 next day
    • Dietary fat load
      supporter · GI -2.4 next day
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • Caffeine
      perturbation · steering -8
    • Enterobacteriaceae elevated
      hidden · steering -7.4
    • Poor-sleep week
      perturbation · steering -3
    • Caffeine
      detractor · GI +4.7 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -6.1supporter · 95%
    • Caffeine
      +4.7detractor · 95%
    • Dietary fat load
      -2.4supporter · 57%
    • Alcohol
      -1.4no signal · 29%
    • Histamine load
      +1.3no signal · 29%
    • Insoluble fibre
      -0.8no signal · 15%
    • Ultra-processed food
      +0.8no signal · 19%
    • Simple carbohydrates
      +0.7no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery ↑20
      • WearableShort sleep window
    • Mucosal barrier integrity ↓10
      • WearableSleep 6.1 h, below personal baseline
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    Microbiome
    Shannon diversity 3.4 · butyrate capacity 45/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    50 ms
    Sleep
    5.8 h
    Steps
    7,959
    Resting HR
    59 bpm
    Daily log: GI score 21, nutritional resilience 71, adherence 99.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
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    P-0255541%S01AD-05no change79
    P-0227734%S05AD-05improved92
    P-0201336%S14BR-03no change94
    P-0228236%S01BR-03no change88
    P-0235435%S01CR-01improved78
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    P-0256540%S09DT-01no change79
    P-0208137%S20DT-01no change88
    P-0246237%S12DT-01improved65
    P-0221834%S01DT-01improved61
    P-0249134%S09DT-01no change65
    P-0241539%S17GI-04improved86