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Patient P-02446

Synthetic patientMETA-24 · Day 168 · 55–64 · F · baseline S04Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
21%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S04
  2. Day 17 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 17.

Primary contributors, last 14 days
  • Toxicity+12
  • Nutritional resilience-9
  • Treatment adherence-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    85 min
    improving · +3.4 vs previous 14 d
    Sleep duration
    Wearable
    7.9 h
    stable · -0.2 vs previous 14 d
    Energy level
    Daily log
    6.2/10
    worsening · -0.4 vs previous 14 d
    Steps
    Wearable
    8,381
    improving · +382 vs previous 14 d
    GI burden
    Companion
    21/100
    worsening · +3.8 vs previous 14 d
    Adherence
    Companion
    83.9 %
    stable · +1.6 vs previous 14 d
    Sleep quality
    Wearable
    65.2/100
    worsening · -5.7 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    130 mg/dL
    stable · +3.9 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards restoration · 63 from the failing basin, 43 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More histamine
      GI -2.2 next day on high-intake days · n 15
    • More protein
      GI -2.1 next day on high-intake days · n 22
    Would not help
    • BR-03 Behavioural Recommendation
      only 27% improved among 11 similar
    • Keep ultra-processed low
      GI +1.6 next day on high-intake days · n 21
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      -2.2supporter · 67%
    • Protein
      -2.1supporter · 77%
    • Ultra-processed food
      +1.6detractor · 58%
    • Insoluble fibre
      +1.2no signal · 37%
    • Simple carbohydrates
      -0.9no signal · 26%
    • Dietary fat load
      -0.5no signal · 18%
    • Caffeine
      -0.2no signal · 15%
    • Alcohol
      -0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling ↑45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Mucosal barrier integrity ↓30
      • MicrobiomeAkkermansia low → thinner mucus layer
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    Microbiome
    Shannon diversity 3.7 · butyrate capacity 71/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    65 ms
    Sleep
    7.7 h
    Steps
    9,063
    Resting HR
    71 bpm
    Daily log: GI score 21, nutritional resilience 62, adherence 84.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0269826%S06ME-01improved71
    P-0221425%S08SC-12no change69
    P-0229326%S15HY-01no change68
    P-0209025%S04——68
    P-0265827%S04——66
    P-0210925%S04——66
    P-0209526%S08——66
    P-0228625%S10——65
    P-0261726%S03——64
    P-0204427%S03——64
    P-0248327%S06BR-03no change64
    P-0257927%S09——64