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Patient P-02449

Synthetic patientMETA-24 · Day 168 · 45–54 · F · baseline S07Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
8%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S07

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • Treatment adherence+4
  • Inflammatory activity-2
  • Toxicity-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    73 min
    worsening · -3.4 vs previous 14 d
    Sleep duration
    Wearable
    8.1 h
    stable · +0.2 vs previous 14 d
    Energy level
    Daily log
    7.7/10
    stable · +0.2 vs previous 14 d
    Steps
    Wearable
    7,079
    worsening · -345 vs previous 14 d
    GI burden
    Companion
    17.9/100
    stable · +0.7 vs previous 14 d
    Adherence
    Companion
    99.6 %
    stable · +1.8 vs previous 14 d
    Sleep quality
    Wearable
    59.7/100
    stable · +2.1 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    130 mg/dL
    stable · +1.5 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 89 from the failing basin, 4 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -3.4 next day on high-intake days · n 22
    Would not help
    • Keep histamine low
      GI +3.7 next day on high-intake days · n 22
    • Keep fat low
      GI +2.4 next day on high-intake days · n 15
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +3.7detractor · 95%
    • Protein
      -3.4supporter · 95%
    • Dietary fat load
      +2.4detractor · 71%
    • Alcohol
      -1.6no signal · 36%
    • Ultra-processed food
      +1.5no signal · 47%
    • Insoluble fibre
      +0.3no signal · 15%
    • Simple carbohydrates
      -0.2no signal · 15%
    • Caffeine
      0no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling ↓45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.4 · butyrate capacity 65/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    43 ms
    Sleep
    7.7 h
    Steps
    6,937
    Resting HR
    69 bpm
    Daily log: GI score 18, nutritional resilience 66, adherence 100.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
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    P-0255550%S01AD-05no change79
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    P-0228246%S01BR-03no change88
    P-0201344%S14BR-03no change94
    P-0219335%S11CR-01improved87
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    P-0256548%S09DT-01no change79
    P-0208147%S20DT-01no change88
    P-0224934%S09DT-01improved100
    P-0251834%S17DT-01improved68
    P-0233733%S18DT-01no change100
    P-0246233%S12DT-01improved65