Patient P-02466

Synthetic patientMETA-24 · Day 173 · 25–34 · M · baseline S20Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

56%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S20

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

GI instability+29
Nutritional resilience-21
Inflammatory activity+13
Treatment adherence-4

What helped?

No interventions yet.

LIFE OS recommendation

Monitoring Escalation ME-01

77%

probability of meaningful tolerance improvement

284 similar trajectories
100% showed improvement
median effect visible after 3 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

67 min

stable · +1.4 vs previous 14 d

Sleep duration

Wearable

5.7 h

stable · -0.2 vs previous 14 d

Energy level

Daily log

5.5/10

stable · -0.2 vs previous 14 d

Steps

Wearable

7,691

stable · -137 vs previous 14 d

GI burden

Companion

37.4/100

worsening · +7.0 vs previous 14 d

Adherence

Companion

91.6 %

stable · -2.9 vs previous 14 d

Sleep quality

Wearable

36.3/100

worsening · -6.0 vs previous 14 d

Glucose, CGM daily mean

CGM

141 mg/dL

stable · +1.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 75 from the failing basin, 20 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -5.2 next day on high-intake days · n 22

Would not help

Keep simple carbs low
GI +5.2 next day on high-intake days · n 17

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Simple carbohydrates
+5.2detractor · 95%
Protein
-5.2supporter · 95%
Caffeine
+1.5no signal · 34%
Ultra-processed food
+1.5no signal · 33%
Insoluble fibre
+1.2no signal · 22%
Dietary fat load
+0.8no signal · 15%
Histamine load
+0.8no signal · 17%
Alcohol
-0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↓20
- WearableShort sleep window
Mucosal barrier integrity ↓10
- WearableSleep 5.7 h, below personal baseline

DNA

Fictional pharmacogenomic panel

CYP2D6 Rapid metabolizer
Expected exposure
GLP1R rs6923761 A
Altered receptor sensitivity

Microbiome

Shannon diversity 2.9 · butyrate capacity 47/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 58 ms
Sleep: 6.4 h
Steps: 8,545
Resting HR: 66 bpm

Daily log: GI score 37, nutritional resilience 55, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02555	37%	S01	AD-05	no change	79
P-02277	34%	S05	AD-05	improved	92
P-02282	40%	S01	BR-03	no change	88
P-02013	37%	S14	BR-03	no change	94
P-02280	31%	S07	BR-03	no change	50
P-02193	36%	S11	CR-01	improved	87
P-02354	33%	S01	CR-01	improved	78
P-02565	40%	S09	DT-01	no change	79
P-02081	39%	S20	DT-01	no change	88
P-02491	35%	S09	DT-01	no change	65
P-02337	33%	S18	DT-01	no change	100
P-02518	33%	S17	DT-01	improved	68