Patient P-02486
Therapy response
Favorable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
15%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S10
- Day 63 ME-01 recommended — Monitoring Escalation ME-01
- Day 64 Patient accepted — Started ME-01 in the companion
- Day 67 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- Toxicity-22
- Inflammatory activity-7
- Nutritional resilience+6
- Treatment adherence+6
- GI instability+5
What helped?
- Monitoring Escalation ME-01Day 63Result: deterioration detected before clinical escalation
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↑25
- WearableResting HR 73 bpm
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.7 · butyrate capacity 52/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 66 ms
- Sleep
- 6.7 h
- Steps
- 6,650
- Resting HR
- 71 bpm
Daily log: GI score 15, nutritional resilience 71, adherence 96.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02277 | 54% | S05 | AD-05 | improved | 92 |
| P-02450 | 47% | S12 | NP-02 | improved | 92 |
| P-02249 | 46% | S09 | DT-01 | improved | 100 |
| P-02464 | 43% | S18 | ME-01 | improved | 68 |
| P-02193 | 42% | S11 | CR-01 | improved | 87 |
| P-02630 | 41% | S17 | NP-02 | improved | 76 |
| P-02667 | 41% | S08 | HY-01 | improved | 77 |
| P-02068 | 40% | S14 | NP-02 | improved | 83 |
| P-02127 | 39% | S11 | SC-12 | improved | 73 |
| P-02415 | 39% | S17 | GI-04 | improved | 86 |
| P-02690 | 36% | S02 | ME-01 | improved | 73 |
| P-02441 | 33% | S11 | SC-12 | improved | 67 |