Patient P-02486

Synthetic patientMETA-24 · Day 171 · 25–34 · F · baseline S10Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

15%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S10
Day 63 ME-01 recommended — Monitoring Escalation ME-01
Day 64 Patient accepted — Started ME-01 in the companion
Day 67 Deterioration detected before clinical escalation — Monitoring Escalation ME-01

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Toxicity-22
Inflammatory activity-7
Nutritional resilience+6
Treatment adherence+6
GI instability+5

What helped?

Monitoring Escalation ME-01Day 63
Result: deterioration detected before clinical escalation

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

51 min

stable · -2.2 vs previous 14 d

Sleep duration

Wearable

6.8 h

stable · +0.0 vs previous 14 d

Energy level

Daily log

7.1/10

stable · +0.2 vs previous 14 d

Steps

Wearable

6,140

stable · -125 vs previous 14 d

GI burden

Companion

14.5/100

improving · -6.8 vs previous 14 d

Adherence

Companion

95.5 %

stable · +0.1 vs previous 14 d

Sleep quality

Wearable

46.8/100

improving · +2.9 vs previous 14 d

Glucose, CGM daily mean

CGM

132 mg/dL

stable · -4.4 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 94 from the failing basin, 9 from restoration.

Good elements to keep

Monitoring Escalation ME-01
intervention · steering +20.7
Butyrate producers intact
hidden · steering +7.5
Protein (supports)
perturbation · steering +7.5
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -4.4 next day

Main detractors to watch

Alcohol
perturbation · steering -8.1
Bacteroides fragilis elevated
hidden · steering -7.4
Low-HRV stretch
perturbation · steering -2.7
Dietary drift
perturbation · steering -2.6
Alcohol
detractor · GI +5 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+5detractor · 95%
Protein
-4.4supporter · 95%
Simple carbohydrates
-1.8no signal · 34%
Caffeine
-1.3no signal · 29%
Histamine load
+1.2no signal · 17%
Ultra-processed food
-0.9no signal · 20%
Dietary fat load
+0.3no signal · 15%
Insoluble fibre
-0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↑25
- WearableResting HR 73 bpm
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
GLP1R rs6923761 A
Altered receptor sensitivity
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.7 · butyrate capacity 52/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 66 ms
Sleep: 6.7 h
Steps: 6,650
Resting HR: 71 bpm

Daily log: GI score 15, nutritional resilience 71, adherence 96.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02277	54%	S05	AD-05	improved	92
P-02555	48%	S01	AD-05	no change	79
P-02282	41%	S01	BR-03	no change	88
P-02013	39%	S14	BR-03	no change	94
P-02193	42%	S11	CR-01	improved	87
P-02354	27%	S01	CR-01	improved	78
P-02249	46%	S09	DT-01	improved	100
P-02081	44%	S20	DT-01	no change	88
P-02337	44%	S18	DT-01	no change	100
P-02565	41%	S09	DT-01	no change	79
P-02462	28%	S12	DT-01	improved	65
P-02218	27%	S01	DT-01	improved	61