Patient P-02488
Synthetic patientMETA-24 · Day 110 · 45–54 · M · baseline S16Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Improving
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
19%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S16
- Day 24 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 24.
Primary contributors, last 14 days
- Nutritional resilience+11
- Treatment adherence-8
- Toxicity-5
- GI instability-4
- Inflammatory activity-2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable75 min
stable · -2.2 vs previous 14 d
Sleep duration
Wearable6.2 h
stable · -0.1 vs previous 14 d
Energy level
Daily log5.4/10
worsening · -0.5 vs previous 14 d
Steps
Wearable8,539
stable · -204 vs previous 14 d
GI burden
Companion24/100
worsening · +3.1 vs previous 14 d
Adherence
Companion86.4 %
stable · -2.0 vs previous 14 d
Sleep quality
Wearable36.2/100
worsening · -3.6 vs previous 14 d
Glucose, CGM daily mean
CGM132 mg/dL
stable · -0.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 66 from the failing basin, 28 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -3.8 next day on high-intake days · n 26
Would not help
- Keep histamine lowGI +4 next day on high-intake days · n 16
- Keep caffeine lowGI +1.8 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+4detractor · 95%
- Protein-3.8supporter · 95%
- Caffeine+1.8detractor · 63%
- Insoluble fibre+1.3no signal · 32%
- Alcohol-0.8no signal · 27%
- Ultra-processed food+0.6no signal · 16%
- Dietary fat load-0.4no signal · 15%
- Simple carbohydrates-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 3.3 · butyrate capacity 68/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 44 ms
- Sleep
- 6.8 h
- Steps
- 8,165
- Resting HR
- 70 bpm
Daily log: GI score 24, nutritional resilience 66, adherence 86.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.