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Patient P-02513

Synthetic patientMETA-24 · Day 120 · 25–34 · M · baseline S16Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S16
  2. Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 22 GI-04 recommended — GI Support Protocol GI-04
  4. Day 23 Patient accepted — Started GI-04 in the companion
  5. Day 31 No meaningful change — GI Support Protocol GI-04

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • GI instability-7
  • Inflammatory activity-6
  • Treatment adherence+3
  • Toxicity+3

What helped?

  • GI Support Protocol GI-04Day 22
    Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
44 min
stable · -0.9 vs previous 14 d
Sleep duration
Wearable
6.9 h
stable · -0.0 vs previous 14 d
Energy level
Daily log
6.1/10
stable · +0.1 vs previous 14 d
Steps
Wearable
5,291
improving · +229 vs previous 14 d
GI burden
Companion
18.8/100
improving · -1.2 vs previous 14 d
Adherence
Companion
94 %
stable · +2.4 vs previous 14 d
Sleep quality
Wearable
38.6/100
improving · +1.9 vs previous 14 d
Glucose, CGM daily mean
CGM
134 mg/dL
stable · +0.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards restoration · 71 from the failing basin, 32 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -3.9 next day on high-intake days · n 26
Would not help
  • GI-04 GI Support Protocol
    already tried, no meaningful change
  • Keep ultra-processed low
    GI +4.2 next day on high-intake days · n 18
  • Keep simple carbs low
    GI +4.1 next day on high-intake days · n 18
  • Keep alcohol low
    GI +4.1 next day on high-intake days · n 20
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Ultra-processed food
    +4.2detractor · 95%
  • Simple carbohydrates
    +4.1detractor · 95%
  • Alcohol
    +4.1detractor · 95%
  • Protein
    -3.9supporter · 95%
  • Dietary fat load
    +3.5detractor · 95%
  • Caffeine
    +3detractor · 95%
  • Histamine load
    +0.4no signal · 15%
  • Insoluble fibre
    +0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Drug metabolism and exposure ↑40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Butyrate / short-chain fatty acid production ↓35
    • MicrobiomeButyrate capacity 32/100
  • Mucosal barrier integrity ↓30
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Inflammatory signalling ↓15
    • WearableHRV 35 ms, trending down
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 1.8 · butyrate capacity 32/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
32 ms
Sleep
7.2 h
Steps
4,838
Resting HR
57 bpm
Daily log: GI score 19, nutritional resilience 64, adherence 94.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0256844%S01——51
P-0230739%S01——55
P-0259839%S01——53
P-0208738%S01BR-03no change40
P-0221838%S01DT-01improved61
P-0268138%S01——51
P-0227636%S01——57
P-0252235%S01BR-03no change40
P-0262035%S01HY-01improved64
P-0243734%S01——64
P-0221733%S01——61
P-0237533%S01——44