700 patients110,866 observations180 daysLIVE

Patient P-02543

Synthetic patientMETA-24 · Day 177 · 65–74 · M · baseline S16Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
25%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S16

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • Nutritional resilience-9
  • GI instability+8
  • Toxicity+6
  • Inflammatory activity+4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    42 min
    worsening · -1.9 vs previous 14 d
    Sleep duration
    Wearable
    7 h
    stable · +0.1 vs previous 14 d
    Energy level
    Daily log
    6.6/10
    stable · -0.1 vs previous 14 d
    Steps
    Wearable
    5,273
    stable · +42 vs previous 14 d
    GI burden
    Companion
    22.5/100
    stable · +0.2 vs previous 14 d
    Adherence
    Companion
    91.9 %
    stable · -1.9 vs previous 14 d
    Sleep quality
    Wearable
    45.1/100
    stable · +2.1 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    129 mg/dL
    stable · +0.7 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 82 from the failing basin, 8 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -3.6 next day on high-intake days · n 20
    Would not help
    • Keep histamine low
      GI +4.1 next day on high-intake days · n 21
    • Keep caffeine low
      GI +2.5 next day on high-intake days · n 24
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +4.1detractor · 95%
    • Protein
      -3.6supporter · 95%
    • Caffeine
      +2.5detractor · 84%
    • Alcohol
      +2no signal · 49%
    • Insoluble fibre
      +1.7no signal · 50%
    • Simple carbohydrates
      -1.1no signal · 26%
    • Dietary fat load
      -0.7no signal · 16%
    • Ultra-processed food
      +0.5no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure 40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Mucosal barrier integrity 30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Inflammatory signalling 20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 4.2 · butyrate capacity 68/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    51 ms
    Sleep
    7.6 h
    Steps
    4,527
    Resting HR
    63 bpm
    Daily log: GI score 23, nutritional resilience 59, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0258958%S0282
    P-0227855%S0779
    P-0249955%S0686
    P-0201554%S1478
    P-0211954%S1686
    P-0225454%S1977
    P-0252654%S1686
    P-0256654%S2081
    P-0261353%S1676
    P-0265053%S02HY-01no change84
    P-0267653%S1580
    P-0225652%S1685