700 patients110,866 observations180 daysLIVE

Patient P-02551

Synthetic patientMETA-24 · Day 172 · 55–64 · M · baseline S18Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
34%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S18
  2. Day 18 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 18.

Primary contributors, last 14 days
  • GI instability+12
  • Treatment adherence+7
  • Toxicity-6
  • Nutritional resilience-5
  • Inflammatory activity-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    24 min
    stable · +0.6 vs previous 14 d
    Sleep duration
    Wearable
    5.3 h
    stable · +0.0 vs previous 14 d
    Energy level
    Daily log
    4.4/10
    worsening · -0.3 vs previous 14 d
    Steps
    Wearable
    3,565
    stable · -53 vs previous 14 d
    GI burden
    Companion
    31.8/100
    worsening · +6.5 vs previous 14 d
    Adherence
    Companion
    97.9 %
    stable · -2.1 vs previous 14 d
    Sleep quality
    Wearable
    20.7/100
    stable · +0.1 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    144 mg/dL
    stable · +0.2 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 66 from the failing basin, 21 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +13.2
    • Butyrate producers intact
      hidden · steering +7.5
    • Histamine load (supports)
      perturbation · steering +5.6
    • Protein
      supporter · GI -6.5 next day
    • Histamine load
      supporter · GI -4 next day
    Main detractors to watch
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • IL6 high-expression variant
      hidden · steering -7.3
    • Ultra-processed food
      perturbation · steering -5.2
    • Dietary drift
      perturbation · steering -2.6
    • Ultra-processed food
      detractor · GI +3 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -6.5supporter · 95%
    • Histamine load
      -4supporter · 60%
    • Ultra-processed food
      +3detractor · 65%
    • Caffeine
      +2.4no signal · 33%
    • Dietary fat load
      -1.9no signal · 33%
    • Alcohol
      -1.7no signal · 27%
    • Simple carbohydrates
      -0.4no signal · 15%
    • Insoluble fibre
      +0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Autonomic recovery 65
      • WearableResting HR 74 bpm
      • Wearable3,565 steps/day
      • WearableShort sleep window
    • Inflammatory signalling 45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Mucosal barrier integrity 40
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.3 h, below personal baseline
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 4.3 · butyrate capacity 52/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    39 ms
    Sleep
    5.7 h
    Steps
    2,873
    Resting HR
    72 bpm
    Daily log: GI score 32, nutritional resilience 56, adherence 98.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0227649%S0157
    P-0230745%S0155
    P-0255045%S0170
    P-0259845%S0153
    P-0235444%S01CR-01improved78
    P-0243740%S0164
    P-0256840%S0151
    P-0221739%S0161
    P-0262039%S01HY-01improved64
    P-0268137%S0151
    P-0221836%S01DT-01improved61
    P-0242434%S0162