Patient P-02552

Synthetic patientMETA-24 · Day 178 · 65–74 · F · baseline S07Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

22%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S07
Day 23 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 28 AD-05 recommended — Adherence Support AD-05
Day 29 Patient accepted — Started AD-05 in the companion
Day 34 No meaningful change — Adherence Support AD-05

What changed?

Trajectory began diverging from predicted response on Day 23.

Primary contributors, last 14 days

Toxicity-11
GI instability+6
Nutritional resilience+5
Treatment adherence+3

What helped?

Adherence Support AD-05Day 28
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

67 min

worsening · -3.6 vs previous 14 d

Sleep duration

Wearable

7.3 h

stable · -0.1 vs previous 14 d

Energy level

Daily log

5.3/10

stable · +0.2 vs previous 14 d

Steps

Wearable

7,432

stable · -170 vs previous 14 d

GI burden

Companion

23.8/100

improving · -3.4 vs previous 14 d

Adherence

Companion

85 %

stable · +2.8 vs previous 14 d

Sleep quality

Wearable

41.8/100

stable · -0.0 vs previous 14 d

Glucose, CGM daily mean

CGM

133 mg/dL

stable · -0.7 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 63 from the failing basin, 49 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -4.4 next day on high-intake days · n 23

Would not help

BR-03 Behavioural Recommendation
only 22% improved among 9 similar
AD-05 Adherence Support
already tried, no meaningful change
Keep alcohol low
GI +3.7 next day on high-intake days · n 15
Keep ultra-processed low
GI +3 next day on high-intake days · n 22

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4.4supporter · 95%
Alcohol
+3.7detractor · 95%
Ultra-processed food
+3detractor · 88%
Simple carbohydrates
+1.3no signal · 29%
Insoluble fibre
+1.3no signal · 34%
Dietary fat load
+1no signal · 22%
Histamine load
-1no signal · 20%
Caffeine
+0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↑40
- DNAIL6 -174 variant raises baseline inflammatory tone
- WearableHRV 29 ms, trending down
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.6 · butyrate capacity 66/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 30 ms
Sleep: 7.1 h
Steps: 7,240
Resting HR: 62 bpm

Daily log: GI score 24, nutritional resilience 64, adherence 85.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02093	34%	S05	AD-05	no change	40
P-02285	33%	S14	AD-05	no change	39
P-02031	29%	S12	AD-05	improved	47
P-02564	46%	S15	BR-03	improved	32
P-02325	39%	S19	BR-03	no change	33
P-02522	35%	S01	BR-03	no change	40
P-02308	32%	S13	BR-03	no change	27
P-02439	32%	S08	BR-03	no change	40
P-02087	31%	S01	BR-03	no change	40
P-02331	31%	S14	BR-03	improved	34
P-02267	29%	S09	BR-03	no change	45
P-02280	25%	S07	BR-03	no change	50