Patient P-02558
Synthetic patientMETA-24 · Day 104 · 45–54 · M · baseline S17Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
8%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S17
- Day 81 HY-01 recommended — Hydration Protocol HY-01
- Day 82 Patient accepted — Started HY-01 in the companion
- Day 86 No meaningful change — Hydration Protocol HY-01
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- GI instability-15
- Inflammatory activity-8
- Toxicity-6
- Nutritional resilience+4
What helped?
- Hydration Protocol HY-01Day 81Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable59 min
stable · +1.6 vs previous 14 d
Sleep duration
Wearable7.6 h
worsening · -0.3 vs previous 14 d
Energy level
Daily log7.6/10
stable · -0.1 vs previous 14 d
Steps
Wearable5,824
stable · +103 vs previous 14 d
GI burden
Companion10.2/100
worsening · +2.1 vs previous 14 d
Adherence
Companion91.5 %
stable · +1.9 vs previous 14 d
Sleep quality
Wearable50.5/100
worsening · -4.0 vs previous 14 d
Glucose, CGM daily mean
CGM126 mg/dL
stable · +3.6 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 94 from the failing basin, 9 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +9.5
- Butyrate producers intacthidden · steering +7.5
- Hydration Protocol HY-01intervention · steering +5.2
- Proteinsupporter · GI -5 next day
Main detractors to watch
- Poor metabolizerhidden · steering -12.7
- Caffeineperturbation · steering -9.2
- Bacteroides fragilis elevatedhidden · steering -7.4
- Alcoholperturbation · steering -5.3
- Caffeinedetractor · GI +6 next day
- Alcoholdetractor · GI +3.2 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Caffeine+6detractor · 95%
- Protein-5supporter · 95%
- Alcohol+3.2detractor · 77%
- Histamine load-2no signal · 35%
- Simple carbohydrates+1.7no signal · 40%
- Ultra-processed food+0.8no signal · 17%
- Dietary fat load+0.3no signal · 15%
- Insoluble fibre-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Inflammatory signalling ↓35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 34 ms, trending down
- Autonomic recovery ↑25
- WearableResting HR 72 bpm
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 4.3 · butyrate capacity 70/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 29 ms
- Sleep
- 7.4 h
- Steps
- 6,299
- Resting HR
- 74 bpm
Daily log: GI score 10, nutritional resilience 70, adherence 92.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02337 | 31% | S18 | DT-01 | no change | 100 |
| P-02249 | 34% | S09 | DT-01 | improved | 100 |
| P-02189 | 35% | S17 | — | — | 96 |
| P-02640 | 34% | S03 | — | — | 96 |
| P-02242 | 36% | S20 | — | — | 95 |
| P-02013 | 39% | S14 | BR-03 | no change | 94 |
| P-02104 | 42% | S15 | — | — | 94 |
| P-02450 | 40% | S12 | NP-02 | improved | 92 |
| P-02304 | 40% | S15 | — | — | 92 |
| P-02277 | 37% | S05 | AD-05 | improved | 92 |
| P-02689 | 33% | S13 | — | — | 91 |
| P-02069 | 44% | S19 | — | — | 91 |