Patient P-02564
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
29%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S15
- Day 22 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 32 BR-03 recommended — Behavioural Recommendation BR-03
- Day 33 Patient accepted — Started BR-03 in the companion
- Day 40 GI symptom burden −17% vs expected — Behavioural Recommendation BR-03
- Day 46 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 22.
Primary contributors, last 14 days
- Toxicity+17
- Inflammatory activity+15
- GI instability+7
- Nutritional resilience-4
What helped?
- Behavioural Recommendation BR-03Day 32Result: symptom burden −17%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 34 ms, trending down
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓20
- WearableShort sleep window
- Mucosal barrier integrity ↓10
- WearableSleep 6.1 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 4.2 · butyrate capacity 52/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 39 ms
- Sleep
- 6.0 h
- Steps
- 4,882
- Resting HR
- 67 bpm
Daily log: GI score 25, nutritional resilience 62, adherence 86.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.