Patient P-02575
Synthetic patientMETA-24 · Day 94 · 55–64 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 69 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 86 ME-01 recommended — Monitoring Escalation ME-01
- Day 87 Patient accepted — Started ME-01 in the companion
- Day 90 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 69.
Primary contributors, last 14 days
- GI instability+14
- Inflammatory activity+9
- Toxicity+9
- Treatment adherence-8
- Nutritional resilience-6
What helped?
- Monitoring Escalation ME-01Day 86Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 91% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable7 min
worsening · -14.4 vs previous 14 d
Sleep duration
Wearable5.9 h
worsening · -0.5 vs previous 14 d
Energy level
Daily log2.6/10
worsening · -1.9 vs previous 14 d
Steps
Wearable939
worsening · -1,666 vs previous 14 d
GI burden
Companion62/100
worsening · +21.1 vs previous 14 d
Adherence
Companion76.2 %
worsening · -6.3 vs previous 14 d
Sleep quality
Wearable22.2/100
worsening · -13.9 vs previous 14 d
Glucose, CGM daily mean
CGM147 mg/dL
worsening · +9.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 50 from the failing basin, 60 from restoration.
Would help
- GI-04 GI Support Protocol84% improved among 50 similar · onset 8 d · confidence 97%
- SC-12 Supportive Compound71% improved among 17 similar · onset 6 d · confidence 80%
- CR-01 Clinician Review100% improved among 8 similar · onset 5 d · confidence 80%
- More proteinGI -5.1 next day on high-intake days · n 20
Would not help
- Keep histamine lowGI +4.8 next day on high-intake days · n 18
- Keep fat lowGI +3.5 next day on high-intake days · n 21
- Keep simple carbs lowGI +2.3 next day on high-intake days · n 29
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.1supporter · 95%
- Histamine load+4.8detractor · 95%
- Dietary fat load+3.5detractor · 95%
- Simple carbohydrates+2.3detractor · 70%
- Ultra-processed food+2.2detractor · 58%
- Alcohol-0.3no signal · 15%
- Insoluble fibre+0.2no signal · 15%
- Caffeine-0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 62 and rising
- WearableSleep 5.9 h, below personal baseline
- Autonomic recovery ↓65
- WearableResting HR 74 bpm
- Wearable939 steps/day
- WearableShort sleep window
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 28/100
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑25
- BloodInflammatory load index 62
- Drug metabolism and exposure ↑20
- BloodToxicity index 57
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.7 · butyrate capacity 28/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 39 ms
- Sleep
- 6.1 h
- Steps
- 911
- Resting HR
- 73 bpm
Daily log: GI score 62, nutritional resilience 39, adherence 76.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02409 | 28% | S01 | SC-12 | no change | 54 |
| P-02054 | 26% | S01 | CR-01 | improved | 57 |
| P-02138 | 24% | S01 | — | — | 79 |
| P-02018 | 23% | S01 | GI-04 | improved | 46 |
| P-02275 | 23% | S01 | — | — | 84 |
| P-02410 | 23% | S01 | GI-04 | improved | 55 |
| P-02437 | 23% | S01 | — | — | 64 |
| P-02550 | 23% | S01 | — | — | 70 |
| P-02598 | 23% | S01 | — | — | 53 |
| P-02204 | 22% | S01 | — | — | 70 |
| P-02276 | 22% | S01 | — | — | 57 |
| P-02307 | 22% | S01 | — | — | 55 |