Patient P-02589

Synthetic patientMETA-24 · Day 168 · 65–74 · M · baseline S02Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Deteriorating

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

23%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S02

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Nutritional resilience-11
Toxicity+10
Inflammatory activity+7
GI instability+6
Treatment adherence+3

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

44 min

worsening · -2.2 vs previous 14 d

Sleep duration

Wearable

7.9 h

stable · -0.2 vs previous 14 d

Energy level

Daily log

6.7/10

worsening · -0.5 vs previous 14 d

Steps

Wearable

4,653

worsening · -230 vs previous 14 d

GI burden

Companion

26.7/100

worsening · +11.9 vs previous 14 d

Adherence

Companion

89.9 %

stable · -1.0 vs previous 14 d

Sleep quality

Wearable

67.2/100

worsening · -7.0 vs previous 14 d

Glucose, CGM daily mean

CGM

126 mg/dL

worsening · +9.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 81 from the failing basin, 12 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -6.4 next day on high-intake days · n 22

Would not help

Keep histamine low
GI +7.8 next day on high-intake days · n 18
Keep ultra-processed low
GI +6.7 next day on high-intake days · n 18

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+7.8detractor · 95%
Ultra-processed food
+6.7detractor · 95%
Protein
-6.4supporter · 95%
Simple carbohydrates
+2no signal · 30%
Insoluble fibre
+1.3no signal · 19%
Alcohol
-0.6no signal · 15%
Dietary fat load
-0.3no signal · 15%
Caffeine
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↑45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Rapid metabolizer
Expected exposure

Microbiome

Shannon diversity 3.2 · butyrate capacity 52/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 50 ms
Sleep: 7.7 h
Steps: 4,871
Resting HR: 63 bpm

Daily log: GI score 27, nutritional resilience 61, adherence 90.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02555	48%	S01	AD-05	no change	79
P-02277	42%	S05	AD-05	improved	92
P-02282	43%	S01	BR-03	no change	88
P-02013	42%	S14	BR-03	no change	94
P-02193	40%	S11	CR-01	improved	87
P-02354	34%	S01	CR-01	improved	78
P-02081	47%	S20	DT-01	no change	88
P-02565	47%	S09	DT-01	no change	79
P-02337	37%	S18	DT-01	no change	100
P-02249	35%	S09	DT-01	improved	100
P-02462	33%	S12	DT-01	improved	65
P-02491	32%	S09	DT-01	no change	65