Patient P-02593
Synthetic patientMETA-24 · Day 172 · 65–74 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Unstable
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 69 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 89 ME-01 recommended — Monitoring Escalation ME-01
- Day 90 Patient accepted — Started ME-01 in the companion
- Day 93 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 69.
Primary contributors, last 14 days
- Toxicity+10
- Treatment adherence-8
- GI instability-7
- Nutritional resilience+4
- Inflammatory activity-2
What helped?
- Monitoring Escalation ME-01Day 89Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 88% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable4 min
improving · +2.6 vs previous 14 d
Sleep duration
Wearable5.2 h
improving · +0.3 vs previous 14 d
Energy level
Daily log1.6/10
improving · +0.2 vs previous 14 d
Steps
Wearable1,369
improving · +170 vs previous 14 d
GI burden
Companion56/100
stable · -1.2 vs previous 14 d
Adherence
Companion37.3 %
improving · +2.0 vs previous 14 d
Sleep quality
Wearable4.3/100
improving · +3.4 vs previous 14 d
Glucose, CGM daily mean
CGM157 mg/dL
stable · +0.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 27 from the failing basin, 61 from restoration.
Would help
- GI-04 GI Support Protocol76% improved among 66 similar · onset 8 d · confidence 94%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 75%
- SC-12 Supportive Compound69% improved among 26 similar · onset 6 d · confidence 75%
- More proteinGI -5.7 next day on high-intake days · n 23
Would not help
- Keep fat lowGI +5.4 next day on high-intake days · n 20
- Keep simple carbs lowGI +3.8 next day on high-intake days · n 19
- Keep ultra-processed lowGI +3.5 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.7supporter · 95%
- Dietary fat load+5.4detractor · 95%
- Simple carbohydrates+3.8detractor · 95%
- Ultra-processed food+3.5detractor · 83%
- Histamine load-1.1no signal · 32%
- Alcohol+0.9no signal · 21%
- Caffeine+0.6no signal · 15%
- Insoluble fibre-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 43/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 56 and rising
- WearableSleep 5.2 h, below personal baseline
- Inflammatory signalling ↓60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 58
- WearableHRV 26 ms, trending down
- Autonomic recovery ↓40
- Wearable1,369 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 62
DNA
Fictional pharmacogenomic panel
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 2.2 · butyrate capacity 43/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 34 ms
- Sleep
- 5.2 h
- Steps
- 1,044
- Resting HR
- 68 bpm
Daily log: GI score 56, nutritional resilience 35, adherence 37.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02018 | 35% | S01 | GI-04 | improved | 46 |
| P-02410 | 31% | S01 | GI-04 | improved | 55 |
| P-02054 | 28% | S01 | CR-01 | improved | 57 |
| P-02409 | 28% | S01 | SC-12 | no change | 54 |
| P-02307 | 18% | S01 | — | — | 55 |
| P-02598 | 18% | S01 | — | — | 53 |
| P-02041 | 17% | S01 | — | — | 27 |
| P-02276 | 17% | S01 | — | — | 57 |
| P-02437 | 17% | S01 | — | — | 64 |
| P-02550 | 17% | S01 | — | — | 70 |
| P-02568 | 17% | S01 | — | — | 51 |
| P-02087 | 16% | S01 | BR-03 | no change | 40 |