Patient P-02631
Synthetic patientMETA-24 · Day 180 · 55–64 · F · baseline S17Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Stable
GI state
Improving
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
57%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S17
- Day 50 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 50.
Primary contributors, last 14 days
- GI instability-6
- Inflammatory activity-5
- Toxicity-4
- Nutritional resilience-2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
69%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 87% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable61 min
stable · +1.0 vs previous 14 d
Sleep duration
Wearable6.1 h
stable · +0.2 vs previous 14 d
Energy level
Daily log3.1/10
improving · +0.1 vs previous 14 d
Steps
Wearable5,986
stable · +52 vs previous 14 d
GI burden
Companion57.8/100
stable · -0.1 vs previous 14 d
Adherence
Companion63.2 %
stable · +0.3 vs previous 14 d
Sleep quality
Wearable17.4/100
improving · +1.6 vs previous 14 d
Glucose, CGM daily mean
CGM150 mg/dL
stable · +2.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 36 from the failing basin, 59 from restoration.
Would help
- GI-04 GI Support Protocol75% improved among 64 similar · onset 8 d · confidence 65%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 70%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 70%
- More proteinGI -4.2 next day on high-intake days · n 22
Would not help
- Keep simple carbs lowGI +4 next day on high-intake days · n 21
- Keep histamine lowGI +3.8 next day on high-intake days · n 17
- Keep fat lowGI +3.6 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.2supporter · 95%
- Simple carbohydrates+4detractor · 95%
- Histamine load+3.8detractor · 95%
- Dietary fat load+3.6detractor · 95%
- Ultra-processed food+3.5detractor · 95%
- Alcohol+2.2detractor · 57%
- Caffeine-0.6no signal · 18%
- Insoluble fibre+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 60
- WearableHRV 22 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 39/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 58 and rising
- WearableSleep 6.1 h, below personal baseline
- Drug metabolism and exposure ↑20
- BloodToxicity index 51
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.8 · butyrate capacity 39/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 21 ms
- Sleep
- 5.9 h
- Steps
- 4,546
- Resting HR
- 72 bpm
Daily log: GI score 58, nutritional resilience 35, adherence 63.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02483 | 22% | S06 | BR-03 | no change | 64 |
| P-02151 | 49% | S04 | CR-01 | improved | 49 |
| P-02025 | 48% | S15 | CR-01 | improved | 61 |
| P-02054 | 44% | S01 | CR-01 | improved | 57 |
| P-02009 | 35% | S08 | CR-01 | improved | 64 |
| P-02154 | 31% | S16 | CR-01 | improved | 57 |
| P-02233 | 31% | S16 | CR-01 | improved | 66 |
| P-02491 | 22% | S09 | DT-01 | no change | 65 |
| P-02274 | 21% | S15 | DT-01 | improved | 50 |
| P-02395 | 21% | S12 | DT-01 | improved | 57 |
| P-02339 | 20% | S03 | DT-01 | improved | 50 |
| P-02462 | 20% | S12 | DT-01 | improved | 65 |