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Patient P-02636

Synthetic patientMETA-24 · Day 173 · 35–44 · F · baseline S06Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
59%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S06
  2. Day 29 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 29.

Primary contributors, last 14 days
  • GI instability+24
  • Inflammatory activity+11
  • Nutritional resilience-11
  • Treatment adherence+5

What helped?

No interventions yet.

    LIFE OS recommendation
    GI Support Protocol GI-04
    47%
    probability of meaningful tolerance improvement
    • 284 similar trajectories
    • 67% showed improvement
    • median effect visible after 8 days
    View similar patientsSimulateAdd to intervention cohortAll evidence

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    45 min
    stable · -0.7 vs previous 14 d
    Sleep duration
    Wearable
    5.7 h
    stable · +0.1 vs previous 14 d
    Energy level
    Daily log
    4.3/10
    stable · +0.1 vs previous 14 d
    Steps
    Wearable
    5,354
    stable · -220 vs previous 14 d
    GI burden
    Companion
    48.2/100
    worsening · +1.5 vs previous 14 d
    Adherence
    Companion
    87.4 %
    stable · +0.2 vs previous 14 d
    Sleep quality
    Wearable
    20.9/100
    improving · +2.0 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    145 mg/dL
    stable · +1.4 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 34 from the failing basin, 60 from restoration.

    Would help
    • GI-04 GI Support Protocol
      67% improved among 18 similar · onset 8 d · confidence 52%
    • DT-01 Dosing / Timing Recommendation
      73% improved among 15 similar · onset 5 d · confidence 63%
    • HY-01 Hydration Protocol
      82% improved among 11 similar · onset 4 d · confidence 63%
    • More protein
      GI -9.2 next day on high-intake days · n 23
    Would not help
    • BR-03 Behavioural Recommendation
      only 30% improved among 10 similar
    • Keep alcohol low
      GI +6.4 next day on high-intake days · n 19
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -9.2supporter · 95%
    • Alcohol
      +6.4detractor · 95%
    • Caffeine
      +1.8no signal · 27%
    • Insoluble fibre
      -1.1no signal · 18%
    • Simple carbohydrates
      -0.7no signal · 15%
    • Dietary fat load
      +0.5no signal · 15%
    • Ultra-processed food
      +0.3no signal · 15%
    • Histamine load
      +0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓30
      • Daily logGI symptom score 48 and rising
      • WearableSleep 5.7 h, below personal baseline
    • Inflammatory signalling ↑25
      • BloodInflammatory load index 42
    • Autonomic recovery ↓20
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.4 · butyrate capacity 62/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    46 ms
    Sleep
    6.2 h
    Steps
    5,940
    Resting HR
    60 bpm
    Daily log: GI score 48, nutritional resilience 55, adherence 87.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
    • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Track each bowel movement today: time, stool form, urgency, overnight waking
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • Electrolyte solution, one sachet after any loose stool
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0229326%S15HY-01no change68
    P-0230926%S09——67
    P-0210926%S04——66
    P-0249127%S09DT-01no change65
    P-0261728%S03——64
    P-0248327%S06BR-03no change64
    P-0204426%S03——64
    P-0237126%S16——64
    P-0257927%S09——64
    P-0248526%S05HY-01improved63
    P-0219126%S18——63
    P-0205027%S04——63