Patient P-02638

Synthetic patientMETA-24 · Day 139 · 35–44 · F · baseline S01Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Deteriorating

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Improving

Discontinuation risk

18%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S01
Day 108 BR-03 recommended — Behavioural Recommendation BR-03
Day 109 Patient accepted — Started BR-03 in the companion
Day 116 GI symptom burden −12% vs expected — Behavioural Recommendation BR-03
Day 122 Tolerance state changed — Unstable → Improving
Day 127 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 127.

Primary contributors, last 14 days

Inflammatory activity+9
GI instability+5
Toxicity+5
Nutritional resilience+4
Treatment adherence+4

What helped?

Behavioural Recommendation BR-03Day 108
Result: symptom burden −12%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

81 min

stable · -1.0 vs previous 14 d

Sleep duration

Wearable

7.2 h

improving · +0.3 vs previous 14 d

Energy level

Daily log

6.3/10

stable · +0.2 vs previous 14 d

Steps

Wearable

8,731

stable · +139 vs previous 14 d

GI burden

Companion

22.5/100

improving · -3.8 vs previous 14 d

Adherence

Companion

91.5 %

worsening · -4.5 vs previous 14 d

Sleep quality

Wearable

58.7/100

improving · +6.1 vs previous 14 d

Glucose, CGM daily mean

CGM

137 mg/dL

stable · -1.3 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 66 from the failing basin, 38 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -4.3 next day on high-intake days · n 26

Would not help

BR-03 Behavioural Recommendation
already tried, no meaningful change

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4.3supporter · 95%
Insoluble fibre
+0.9no signal · 25%
Caffeine
+0.9no signal · 28%
Alcohol
-0.8no signal · 22%
Dietary fat load
-0.6no signal · 15%
Ultra-processed food
-0.6no signal · 20%
Simple carbohydrates
-0.2no signal · 15%
Histamine load
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Autonomic recovery ↓25
- WearableResting HR 76 bpm
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.3 · butyrate capacity 69/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 69 ms
Sleep: 7.3 h
Steps: 9,083
Resting HR: 74 bpm

Daily log: GI score 23, nutritional resilience 70, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02087	45%	S01	BR-03	no change	40
P-02681	39%	S01	—	—	51
P-02218	35%	S01	DT-01	improved	61
P-02522	34%	S01	BR-03	no change	40
P-02620	34%	S01	HY-01	improved	64
P-02217	33%	S01	—	—	61
P-02276	32%	S01	—	—	57
P-02568	32%	S01	—	—	51
P-02375	30%	S01	—	—	44
P-02424	30%	S01	—	—	62
P-02437	30%	S01	—	—	64
P-02041	29%	S01	—	—	27