Patient P-02657
Synthetic patientMETA-24 · Day 180 · 65–74 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
94%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 72 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 72.
Primary contributors, last 14 days
- Toxicity-14
- Inflammatory activity-13
- Nutritional resilience+13
- GI instability-10
- Treatment adherence+3
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 87% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable33 min
stable · +0.3 vs previous 14 d
Sleep duration
Wearable6 h
stable · -0.1 vs previous 14 d
Energy level
Daily log2.8/10
improving · +0.1 vs previous 14 d
Steps
Wearable4,441
stable · +82 vs previous 14 d
GI burden
Companion66.3/100
stable · +1.3 vs previous 14 d
Adherence
Companion42.3 %
stable · +1.5 vs previous 14 d
Sleep quality
Wearable24.8/100
worsening · -1.9 vs previous 14 d
Glucose, CGM daily mean
CGM155 mg/dL
stable · +2.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 22 from the failing basin, 70 from restoration.
Would help
- GI-04 GI Support Protocol75% improved among 64 similar · onset 8 d · confidence 95%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 71%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 71%
- More proteinGI -4.3 next day on high-intake days · n 20
Would not help
- Keep fat lowGI +4.4 next day on high-intake days · n 23
- Keep histamine lowGI +4.2 next day on high-intake days · n 21
- Keep fibre lowGI +3.4 next day on high-intake days · n 16
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.4detractor · 95%
- Protein-4.3supporter · 95%
- Histamine load+4.2detractor · 95%
- Insoluble fibre+3.4detractor · 85%
- Alcohol+1.8detractor · 56%
- Simple carbohydrates-1.6no signal · 42%
- Ultra-processed food+0.5no signal · 15%
- Caffeine-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 66 and rising
- WearableSleep 6.0 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 24/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑45
- WearableResting HR 73 bpm
- WearableShort sleep window
- Inflammatory signalling ↓25
- BloodInflammatory load index 58
- Drug metabolism and exposure ↑20
- BloodToxicity index 43
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 24/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 44 ms
- Sleep
- 5.5 h
- Steps
- 2,777
- Resting HR
- 75 bpm
Daily log: GI score 66, nutritional resilience 38, adherence 42.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02483 | 19% | S06 | BR-03 | no change | 64 |
| P-02087 | 18% | S01 | BR-03 | no change | 40 |
| P-02025 | 33% | S15 | CR-01 | improved | 61 |
| P-02151 | 32% | S04 | CR-01 | improved | 49 |
| P-02054 | 29% | S01 | CR-01 | improved | 57 |
| P-02009 | 27% | S08 | CR-01 | improved | 64 |
| P-02154 | 27% | S16 | CR-01 | improved | 57 |
| P-02233 | 25% | S16 | CR-01 | improved | 66 |
| P-02395 | 20% | S12 | DT-01 | improved | 57 |
| P-02339 | 19% | S03 | DT-01 | improved | 50 |
| P-02491 | 19% | S09 | DT-01 | no change | 65 |
| P-02274 | 18% | S15 | DT-01 | improved | 50 |