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Patient P-02673

Synthetic patientMETA-24 · Day 160 · 65–74 · M · baseline S19Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
29%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S19
  2. Day 14 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • Nutritional resilience-8
  • GI instability+5
  • Toxicity+5
  • Treatment adherence-4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    71 min
    stable · +2.3 vs previous 14 d
    Sleep duration
    Wearable
    8.2 h
    stable · +0.1 vs previous 14 d
    Energy level
    Daily log
    5.9/10
    stable · +0.1 vs previous 14 d
    Steps
    Wearable
    8,184
    stable · +94 vs previous 14 d
    GI burden
    Companion
    29.9/100
    worsening · +2.2 vs previous 14 d
    Adherence
    Companion
    92.1 %
    stable · +0.8 vs previous 14 d
    Sleep quality
    Wearable
    72.9/100
    stable · +2.3 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    121 mg/dL
    stable · -2.4 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 65 from the failing basin, 23 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -5.7 next day on high-intake days · n 19
    Would not help
    • Keep simple carbs low
      GI +4.8 next day on high-intake days · n 25
    • Keep histamine low
      GI +4.1 next day on high-intake days · n 25
    • Keep ultra-processed low
      GI +3.2 next day on high-intake days · n 21
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -5.7supporter · 95%
    • Simple carbohydrates
      +4.8detractor · 95%
    • Histamine load
      +4.1detractor · 95%
    • Ultra-processed food
      +3.2detractor · 89%
    • Insoluble fibre
      +2.2no signal · 40%
    • Dietary fat load
      +1.6no signal · 35%
    • Caffeine
      +1.5no signal · 35%
    • Alcohol
      +0.4no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity 30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Inflammatory signalling 25
      • DNAIL6 -174 variant raises baseline inflammatory tone
    • Butyrate / short-chain fatty acid production 25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2.8 · butyrate capacity 77/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    66 ms
    Sleep
    7.9 h
    Steps
    8,942
    Resting HR
    66 bpm
    Daily log: GI score 30, nutritional resilience 57, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0235331%S0483
    P-0247831%S1979
    P-0235434%S01CR-01improved78
    P-0204836%S0277
    P-0236031%S1277
    P-0213531%S2077
    P-0238832%S1175
    P-0244332%S1875
    P-0252032%S0675
    P-0243433%S1474
    P-0238632%S0973
    P-0236544%S0872