Patient P-02692
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
11%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S16
- Day 26 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 26.
Primary contributors, last 14 days
- Toxicity+10
- Nutritional resilience-9
- Treatment adherence-5
- GI instability-4
- Inflammatory activity+4
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable60 min
improving · +3.0 vs previous 14 d
Sleep duration
Wearable7.7 h
stable · -0.1 vs previous 14 d
Energy level
Daily log5.9/10
stable · -0.0 vs previous 14 d
Steps
Wearable6,528
improving · +440 vs previous 14 d
GI burden
Companion13.1/100
worsening · +2.8 vs previous 14 d
Adherence
Companion85.5 %
stable · +0.3 vs previous 14 d
Sleep quality
Wearable60.3/100
stable · -1.6 vs previous 14 d
Glucose, CGM daily mean
CGM127 mg/dL
stable · +0.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 72 from the failing basin, 39 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -5.1 next day on high-intake days · n 24
Would not help
- BR-03 Behavioural Recommendationonly 22% improved among 9 similar
- Keep histamine lowGI +5 next day on high-intake days · n 23
- Keep ultra-processed lowGI +2.5 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.1supporter · 95%
- Histamine load+5detractor · 95%
- Ultra-processed food+2.5detractor · 58%
- Simple carbohydrates-1.3no signal · 32%
- Alcohol+0.9no signal · 23%
- Dietary fat load+0.2no signal · 15%
- Insoluble fibre+0.2no signal · 15%
- Caffeine+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 4.2 · butyrate capacity 70/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 36 ms
- Sleep
- 7.3 h
- Steps
- 5,050
- Resting HR
- 63 bpm
Daily log: GI score 13, nutritional resilience 64, adherence 86.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.