Patient P-02698
Therapy response
Improving
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Improving
Discontinuation risk
16%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S06
- Day 81 ME-01 recommended — Monitoring Escalation ME-01
- Day 82 Patient accepted — Started ME-01 in the companion
- Day 85 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- Inflammatory activity+5
- Nutritional resilience+5
- GI instability+3
- Toxicity+2
What helped?
- Monitoring Escalation ME-01Day 81Result: deterioration detected before clinical escalation
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable40 min
improving · +1.1 vs previous 14 d
Sleep duration
Wearable7.1 h
stable · +0.0 vs previous 14 d
Energy level
Daily log5.8/10
stable · +0.1 vs previous 14 d
Steps
Wearable4,352
improving · +262 vs previous 14 d
GI burden
Companion15.8/100
improving · -0.9 vs previous 14 d
Adherence
Companion93.5 %
improving · +4.1 vs previous 14 d
Sleep quality
Wearable51.9/100
stable · -1.0 vs previous 14 d
Glucose, CGM daily mean
CGM130 mg/dL
stable · -1.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 82 from the failing basin, 8 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +8.4
- Butyrate producers intacthidden · steering +7.5
- Monitoring Escalation ME-01intervention · steering +1.5
- Proteinsupporter · GI -3.9 next day
Main detractors to watch
- Poor metabolizerhidden · steering -12.7
- FUT2 non-secretorhidden · steering -10.6
- Caffeineperturbation · steering -5.2
- Histamine loadperturbation · steering -5.1
- Caffeinedetractor · GI +2.9 next day
- Histamine loaddetractor · GI +2.8 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-3.9supporter · 95%
- Caffeine+2.9detractor · 95%
- Histamine load+2.8detractor · 95%
- Dietary fat load+1.4no signal · 39%
- Simple carbohydrates-0.9no signal · 28%
- Insoluble fibre-0.4no signal · 15%
- Alcohol-0.4no signal · 15%
- Ultra-processed food+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 4.2 · butyrate capacity 79/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 42 ms
- Sleep
- 6.5 h
- Steps
- 3,022
- Resting HR
- 65 bpm
Daily log: GI score 16, nutritional resilience 68, adherence 94.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.