Emergent Cluster EC-01NEW

30 patients

Response builds, then fades from the second month without a toxicity signal.

Emerges around

Day 60

Detectable by LIFE OS

Day 46

Median clinical recognition

Day 86

Potential lead time

40 days

Average trajectory of the cluster

mean of 30 trajectories · dashed = model expectation at baseline

solid = observed · dashed = predicted

AD-05 appears associated with improved persistence among similar patients (+14% persistence, −2% symptom burden in synthetic history).