Patient P-01318
Therapy response
Unstable
Tolerance
Stable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Unstable
Discontinuation risk
84%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 45 SC-12 recommended — Supportive Compound SC-12
- Day 46 Patient accepted — Started SC-12 in the companion
- Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 52 GI symptom burden −15% vs expected — Supportive Compound SC-12
- Day 54 GI-04 recommended — GI Support Protocol GI-04
- Day 55 Patient accepted — Started GI-04 in the companion
- Day 58 Tolerance state changed — Unstable → Improving
- Day 63 GI symptom burden −34% vs expected — GI Support Protocol GI-04
- Day 69 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 48.
Primary contributors, last 14 days
- GI instability+14
- Inflammatory activity+8
- Treatment adherence-8
- Nutritional resilience-7
- Toxicity-2
What helped?
- Supportive Compound SC-12Day 45Result: symptom burden −15%
- GI Support Protocol GI-04Day 54Result: symptom burden −34%
LIFE OS recommendation
Dietary Support Protocol NP-02
60%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 53 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 23/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑25
- BloodInflammatory load index 56
- Autonomic recovery ↓25
- WearableResting HR 74 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 45
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.3 · butyrate capacity 23/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 57 ms
- Sleep
- 6.2 h
- Steps
- 5,103
- Resting HR
- 73 bpm
Daily log: GI score 53, nutritional resilience 37, adherence 46.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01539 | 46% | S14 | GI-04 | improved | 43 |
| P-01436 | 45% | S14 | GI-04 | improved | 38 |
| P-01423 | 44% | S19 | GI-04 | improved | 44 |
| P-01458 | 44% | S14 | GI-04 | improved | 44 |
| P-01356 | 43% | S14 | GI-04 | improved | 42 |
| P-01505 | 43% | S14 | NP-02 | improved | 41 |
| P-01603 | 42% | S14 | GI-04 | improved | 40 |
| P-01713 | 42% | S04 | GI-04 | improved | 46 |
| P-01349 | 41% | S14 | GI-04 | improved | 38 |
| P-01494 | 41% | S14 | GI-04 | improved | 42 |
| P-01452 | 40% | S02 | GI-04 | improved | 46 |
| P-01559 | 40% | S06 | GI-04 | improved | 42 |