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Patient P-01319

Synthetic patientNBL-101 · Day 114 · 25–34 · M · baseline S02Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
4%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S02

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • GI instability-7
  • Treatment adherence+4
  • Toxicity+4
  • Inflammatory activity-2
  • Nutritional resilience+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    5.4/100
    improving · -7.9 vs previous 14 d
    Toxicity
    Blood
    11.7/100
    worsening · +2.2 vs previous 14 d
    Sleep quality
    Wearable
    58/100
    improving · +7.1 vs previous 14 d
    Energy level
    Daily log
    6.8/10
    stable · -0.0 vs previous 14 d
    Stress level
    Daily log
    2.6/10
    improving · -0.3 vs previous 14 d
    Steps
    Wearable
    7,992
    improving · +334 vs previous 14 d
    Adherence
    Companion
    91.7 %
    stable · +0.2 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards restoration · 100 from the failing basin, 15 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep histamine low
      GI +7.4 next day on high-intake days · n 17
    • Keep fat low
      GI +4.5 next day on high-intake days · n 19
    • Keep alcohol low
      GI +4.3 next day on high-intake days · n 8
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +7.4detractor · 95%
    • Dietary fat load
      +4.5detractor · 90%
    • Alcohol
      +4.3detractor · 73%
    • Simple carbohydrates
      -0.8no signal · 15%
    • Spicy / capsaicin
      +0.8no signal · 15%
    • Insoluble fibre
      +0.3no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑75
      • DNACYP2D6 poor metabolizer → higher exposure
      • DNADPYD *2A → slower clearance
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Inflammatory signalling ↓20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.7 · butyrate capacity 79/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    69 ms
    Sleep
    7.4 h
    Steps
    8,178
    Resting HR
    65 bpm
    Daily log: GI score 5, nutritional resilience 77, adherence 92.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
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    P-0176641%S05AD-05no change90
    P-0154123%S09AD-05no change43
    P-0180423%S19AD-05improved61
    P-0132941%S08BR-03improved79
    P-0167740%S05BR-03no change86
    P-0149535%S07BR-03improved85
    P-0146823%S06BR-03no change41
    P-0168923%S13BR-03no change50
    P-0165437%S08CR-01improved85
    P-0147940%S15DT-01improved84
    P-0185535%S04DT-01improved73
    P-0172429%S10DT-01improved63