Patient P-01341
Synthetic patientNBL-101 · Day 97 · 65–74 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Stable
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
64%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 GI symptom burden −14% vs expected — Dietary Support Protocol NP-02
- Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 48 Tolerance state changed — Unstable → Improving
- Day 50 GI-04 recommended — GI Support Protocol GI-04
- Day 51 Patient accepted — Started GI-04 in the companion
- Day 59 GI symptom burden −37% vs expected — GI Support Protocol GI-04
- Day 65 Tolerance state changed — Unstable → Improving
- Day 67 ME-01 recommended — Monitoring Escalation ME-01
- Day 68 Patient accepted — Started ME-01 in the companion
- Day 71 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 48.
Primary contributors, last 14 days
- Toxicity+17
- Nutritional resilience-6
- Treatment adherence+6
- GI instability+4
- Inflammatory activity+4
What helped?
- Dietary Support Protocol NP-02Day 31Result: symptom burden −14%
- GI Support Protocol GI-04Day 50Result: symptom burden −37%
- Monitoring Escalation ME-01Day 67Result: deterioration detected before clinical escalation
LIFE OS recommendation
Supportive Compound SC-12
71%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 81% showed improvement
- median effect visible after 6 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion46.3/100
worsening · +3.4 vs previous 14 d
Toxicity
Blood44.1/100
worsening · +5.0 vs previous 14 d
Sleep quality
Wearable19.9/100
worsening · -5.5 vs previous 14 d
Energy level
Daily log4/10
worsening · -0.5 vs previous 14 d
Stress level
Daily log7.3/10
worsening · +0.5 vs previous 14 d
Steps
Wearable2,401
worsening · -425 vs previous 14 d
Adherence
Companion59.5 %
worsening · -8.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 37 from the failing basin, 50 from restoration.
Would help
Would not help
- Keep simple carbs lowGI +5.3 next day on high-intake days · n 23
- Keep fat lowGI +4.9 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+5.3detractor · 95%
- Dietary fat load+4.9detractor · 95%
- Spicy / capsaicin+1.9no signal · 44%
- Alcohol+0.2no signal · 15%
- Histamine load-0.1no signal · 15%
- Insoluble fibre0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 49
- WearableHRV 19 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 26/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓65
- WearableResting HR 73 bpm
- Wearable2,401 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 46 and rising
- WearableSleep 5.9 h, below personal baseline
- Drug metabolism and exposure ↑20
- BloodToxicity index 44
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 26/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 21 ms
- Sleep
- 6.7 h
- Steps
- 3,853
- Resting HR
- 72 bpm
Daily log: GI score 46, nutritional resilience 43, adherence 60.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01688 | 38% | S01 | GI-04 | improved | 40 |
| P-01327 | 35% | S01 | GI-04 | improved | 56 |
| P-01310 | 28% | S01 | — | — | 57 |
| P-01813 | 28% | S01 | NP-02 | no change | 40 |
| P-01877 | 25% | S01 | CR-01 | improved | 67 |
| P-01823 | 24% | S01 | — | — | 57 |
| P-01846 | 24% | S01 | — | — | 37 |
| P-01604 | 23% | S01 | — | — | 71 |
| P-01635 | 35% | S02 | GI-04 | improved | 49 |
| P-01452 | 33% | S02 | GI-04 | improved | 46 |
| P-01459 | 27% | S02 | — | — | 51 |
| P-01499 | 24% | S02 | — | — | 65 |