Patient P-01813
Therapy response
Unstable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S01
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 No meaningful change — Dietary Support Protocol NP-02
- Day 49 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 66 ME-01 recommended — Monitoring Escalation ME-01
- Day 67 Patient accepted — Started ME-01 in the companion
- Day 70 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 49.
Primary contributors, last 14 days
- GI instability+20
- Inflammatory activity+14
- Nutritional resilience-7
- Toxicity-7
What helped?
- Dietary Support Protocol NP-02Day 31Result: no meaningful change
- Monitoring Escalation ME-01Day 66Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
91%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 40/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓45
- WearableResting HR 74 bpm
- Wearable300 steps/day
- Inflammatory signalling ↑40
- BloodInflammatory load index 61
- WearableHRV 24 ms, trending down
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 68 and rising
- Drug metabolism and exposure ↑20
- BloodToxicity index 46
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 40/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 25 ms
- Sleep
- 6.6 h
- Steps
- 784
- Resting HR
- 74 bpm
Daily log: GI score 68, nutritional resilience 36, adherence 46.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01760 | 52% | S14 | — | — | 42 |
| P-01655 | 50% | S14 | GI-04 | no change | 29 |
| P-01802 | 50% | S20 | NP-02 | improved | 42 |
| P-01824 | 50% | S14 | — | — | 42 |
| P-01619 | 48% | S14 | GI-04 | worsened | 38 |
| P-01739 | 48% | S14 | ME-01 | improved | 44 |
| P-01866 | 48% | S14 | — | — | 40 |
| P-01407 | 47% | S14 | NP-02 | no change | 44 |
| P-01605 | 47% | S14 | ME-01 | improved | 41 |
| P-01656 | 47% | S14 | ME-01 | improved | 41 |
| P-01737 | 47% | S14 | — | — | 28 |
| P-01776 | 47% | S16 | NP-02 | no change | 47 |