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Patient P-01342

Synthetic patientNBL-101 · Day 111 · 65–74 · M · baseline S11Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
22%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S11
  2. Day 11 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 14 DT-01 recommended — Dosing / Timing Recommendation DT-01
  4. Day 15 Patient accepted — Started DT-01 in the companion
  5. Day 20 GI symptom burden −14% vs expected — Dosing / Timing Recommendation DT-01
  6. Day 26 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 11.

Primary contributors, last 14 days
  • Toxicity+13
  • Nutritional resilience-6
  • Inflammatory activity+3
  • GI instability+2

What helped?

  • Dosing / Timing Recommendation DT-01Day 14
    Result: symptom burden −14%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
29.4/100
stable · -0.5 vs previous 14 d
Toxicity
Blood
21.3/100
worsening · +3.7 vs previous 14 d
Sleep quality
Wearable
51.2/100
improving · +4.7 vs previous 14 d
Energy level
Daily log
4.9/10
stable · -0.2 vs previous 14 d
Stress level
Daily log
4.1/10
stable · -0.1 vs previous 14 d
Steps
Wearable
7,166
stable · +196 vs previous 14 d
Adherence
Companion
95.4 %
stable · +3.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 58 from the failing basin, 33 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
Would not help
  • Keep fat low
    GI +4.3 next day on high-intake days · n 18
  • Keep simple carbs low
    GI +3.9 next day on high-intake days · n 21
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Dietary fat load
    +4.3detractor · 95%
  • Simple carbohydrates
    +3.9detractor · 95%
  • Spicy / capsaicin
    -1.7no signal · 47%
  • Histamine load
    -1.5no signal · 35%
  • Insoluble fibre
    +0.3no signal · 15%
  • Alcohol
    0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Butyrate / short-chain fatty acid production ↓60
    • MicrobiomeButyrate capacity 40/100
    • MicrobiomeF. prausnitzii depleted
  • Drug metabolism and exposure ↑35
    • DNADPYD *2A → slower clearance
  • Mucosal barrier integrity ↓30
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Inflammatory signalling ↑20
    • MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
  • DPYD *2A heterozygous
    Slower drug clearance
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 2.8 · butyrate capacity 40/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
41 ms
Sleep
7.8 h
Steps
6,745
Resting HR
59 bpm
Daily log: GI score 29, nutritional resilience 56, adherence 95.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0142027%S03——85
P-0141126%S18——84
P-0166527%S06——83
P-0132426%S02——83
P-0143526%S03——82
P-0138429%S08——82
P-0146027%S12——82
P-0152527%S19——82
P-0177028%S13——82
P-0167627%S03——81
P-0180330%S11——81
P-0148427%S18——81